Cruz P - Search Results

1

Recombinant AAV serotype and capsid mutant comparison for pulmonary gene transfer of alpha-1-antitrypsin using invasive and noninvasive delivery.

Liqun Wang R, McLaughlin T, Cossette T, Tang Q, Foust K, Campbell-Thompson M, Martino A, Cruz P, Loiler S, Mueller C, Flotte TR. Liqun Wang R, et al. Among authors: cruz p. Mol Ther. 2009 Jan;17(1):81-7. doi: 10.1038/mt.2008.217. Epub 2008 Oct 21. Mol Ther. 2009. PMID: 18941444 Free PMC article.

2

In vivo post-transcriptional gene silencing of alpha-1 antitrypsin by adeno-associated virus vectors expressing siRNA.

Cruz PE, Mueller C, Cossette TL, Golant A, Tang Q, Beattie SG, Brantly M, Campbell-Thompson M, Blomenkamp KS, Teckman JH, Flotte TR. Cruz PE, et al. Lab Invest. 2007 Sep;87(9):893-902. doi: 10.1038/labinvest.3700629. Epub 2007 Jun 25. Lab Invest. 2007. PMID: 17592477 Free article.

3

The promise of gene therapy for the treatment of alpha-1 antitrypsin deficiency.

Cruz PE, Mueller C, Flotte TR. Cruz PE, et al. Pharmacogenomics. 2007 Sep;8(9):1191-8. doi: 10.2217/14622416.8.9.1191. Pharmacogenomics. 2007. PMID: 17924834 Review.

4

Localized gene expression following administration of adeno-associated viral vectors via pancreatic ducts.

Loiler SA, Tang Q, Clarke T, Campbell-Thompson ML, Chiodo V, Hauswirth W, Cruz P, Perret-Gentil M, Atkinson MA, Ramiya VK, Flotte TR. Loiler SA, et al. Among authors: cruz p. Mol Ther. 2005 Sep;12(3):519-27. doi: 10.1016/j.ymthe.2005.04.017. Mol Ther. 2005. PMID: 15979413 Free article.

5

Recombinant adeno-associated virus-mediated gene transfer for the potential therapy of adenosine deaminase-deficient severe combined immune deficiency.

Silver JN, Elder M, Conlon T, Cruz P, Wright AJ, Srivastava A, Flotte TR. Silver JN, et al. Among authors: cruz p. Hum Gene Ther. 2011 Aug;22(8):935-49. doi: 10.1089/hum.2010.121. Epub 2011 Mar 13. Hum Gene Ther. 2011. PMID: 21142972 Free PMC article.

6

N-glycosylation augmentation of the cystic fibrosis epithelium improves Pseudomonas aeruginosa clearance.

Martino AT, Mueller C, Braag S, Cruz PE, Campbell-Thompson M, Jin S, Flotte TR. Martino AT, et al. Am J Respir Cell Mol Biol. 2011 Jun;44(6):824-30. doi: 10.1165/rcmb.2009-0285OC. Epub 2010 Aug 6. Am J Respir Cell Mol Biol. 2011. PMID: 20693405 Free PMC article.

7

Effects of CFTR, interleukin-10, and Pseudomonas aeruginosa on gene expression profiles in a CF bronchial epithelial cell Line.

Virella-Lowell I, Herlihy JD, Liu B, Lopez C, Cruz P, Muller C, Baker HV, Flotte TR. Virella-Lowell I, et al. Among authors: cruz p. Mol Ther. 2004 Sep;10(3):562-73. doi: 10.1016/j.ymthe.2004.06.215. Mol Ther. 2004. PMID: 15336656 Free article.

8

alpha-1 antitrypsin inhibits caspase-3 activity, preventing lung endothelial cell apoptosis.

Petrache I, Fijalkowska I, Medler TR, Skirball J, Cruz P, Zhen L, Petrache HI, Flotte TR, Tuder RM. Petrache I, et al. Among authors: cruz p. Am J Pathol. 2006 Oct;169(4):1155-66. doi: 10.2353/ajpath.2006.060058. Am J Pathol. 2006. PMID: 17003475 Free PMC article.

9

Widespread and efficient transduction of spinal cord and brain following neonatal AAV injection and potential disease modifying effect in ALS mice.

Ayers JI, Fromholt S, Sinyavskaya O, Siemienski Z, Rosario AM, Li A, Crosby KW, Cruz PE, DiNunno NM, Janus C, Ceballos-Diaz C, Borchelt DR, Golde TE, Chakrabarty P, Levites Y. Ayers JI, et al. Among authors: cruz pe. Mol Ther. 2015 Jan;23(1):53-62. doi: 10.1038/mt.2014.180. Epub 2014 Sep 17. Mol Ther. 2015. PMID: 25228069 Free PMC article.

10

Cellular fusion for gene delivery to SCA1 affected Purkinje neurons.

Chen KA, Cruz PE, Lanuto DJ, Flotte TR, Borchelt DR, Srivastava A, Zhang J, Steindler DA, Zheng T. Chen KA, et al. Mol Cell Neurosci. 2011 May;47(1):61-70. doi: 10.1016/j.mcn.2011.03.003. Epub 2011 Mar 17. Mol Cell Neurosci. 2011. PMID: 21420496 Free PMC article.

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