Rose-John S - Search Results

1

IL-6 transsignalling modulates the early effector phase of EAE and targets the blood-brain barrier.

Linker RA, Lühder F, Kallen KJ, Lee DH, Engelhardt B, Rose-John S, Gold R. Linker RA, et al. J Neuroimmunol. 2008 Dec 15;205(1-2):64-72. doi: 10.1016/j.jneuroim.2008.09.007. Epub 2008 Oct 23. J Neuroimmunol. 2008. PMID: 18950871

2

I. A bioactive designer cytokine for human hematopoietic progenitor cell expansion.

Fischer M, Goldschmitt J, Peschel C, Brakenhoff JP, Kallen KJ, Wollmer A, Grötzinger J, Rose-John S. Fischer M, et al. Nat Biotechnol. 1997 Feb;15(2):142-5. doi: 10.1038/nbt0297-142. Nat Biotechnol. 1997. PMID: 9035138

3

A new type of cytokine receptor antagonist directly targeting gp130.

Renné C, Kallen KJ, Müllberg J, Jostock T, Grötzinger J, Rose-John S. Renné C, et al. J Biol Chem. 1998 Oct 16;273(42):27213-9. doi: 10.1074/jbc.273.42.27213. J Biol Chem. 1998. PMID: 9765242 Free article.

4

Immunoadhesins of interleukin-6 and the IL-6/soluble IL-6R fusion protein hyper-IL-6.

Jostock T, Blinn G, Renné C, Kallen KJ, Rose-John S, Müllberg J. Jostock T, et al. J Immunol Methods. 1999 Mar 4;223(2):171-83. doi: 10.1016/s0022-1759(98)00218-x. J Immunol Methods. 1999. PMID: 10089096

5

Receptor recognition sites of cytokines are organized as exchangeable modules. Transfer of the leukemia inhibitory factor receptor-binding site from ciliary neurotrophic factor to interleukin-6.

Kallen KJ, Grötzinger J, Lelièvre E, Vollmer P, Aasland D, Renné C, Müllberg J, Myer zum Büschenfelde KH, Gascan H, Rose-John S. Kallen KJ, et al. J Biol Chem. 1999 Apr 23;274(17):11859-67. doi: 10.1074/jbc.274.17.11859. J Biol Chem. 1999. PMID: 10207005 Free article.

6

IL-6 type cytokine receptor complexes: hexamer, tetramer or both?

Grötzinger J, Kernebeck T, Kallen KJ, Rose-John S. Grötzinger J, et al. Biol Chem. 1999 Jul-Aug;380(7-8):803-13. doi: 10.1515/BC.1999.100. Biol Chem. 1999. PMID: 10494829 Review.

7

New perspectives on the design of cytokines and growth factors.

Kallen KJ, Grötzinger J, Rose-John S. Kallen KJ, et al. Trends Biotechnol. 2000 Nov;18(11):455-61. doi: 10.1016/s0167-7799(00)01492-x. Trends Biotechnol. 2000. PMID: 11058786 Review.

8

Recognition sequences and structural elements contribute to shedding susceptibility of membrane proteins.

Althoff K, Müllberg J, Aasland D, Voltz N, Kallen K, Grötzinger J, Rose-John S. Althoff K, et al. Biochem J. 2001 Feb 1;353(Pt 3):663-72. doi: 10.1042/0264-6021:3530663. Biochem J. 2001. PMID: 11171064 Free PMC article.

9

The upper cytokine-binding module and the Ig-like domain of the leukaemia inhibitory factor (LIF) receptor are sufficient for a functional LIF receptor complex.

Aasland D, Oppmann B, Grötzinger J, Rose-John S, Kallen KJ. Aasland D, et al. J Mol Biol. 2002 Jan 25;315(4):637-46. doi: 10.1006/jmbi.2001.5282. J Mol Biol. 2002. PMID: 11812136

10

The human interleukin-6 (IL-6) receptor exists as a preformed dimer in the plasma membrane.

Schuster B, Meinert W, Rose-John S, Kallen KJ. Schuster B, et al. FEBS Lett. 2003 Mar 13;538(1-3):113-6. doi: 10.1016/s0014-5793(03)00154-6. FEBS Lett. 2003. PMID: 12633863 Free article.

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