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SC-49992--a potent and specific inhibitor of platelet aggregation.
Nicholson NS, Panzer-Knodle SG, King LW, Taite BB, Keller BT, Tjoeng FS, Engleman VW, Giorgio TD, Feigen LP. Nicholson NS, et al. Among authors: panzer knodle sg. Thromb Res. 1994 Jun 1;74(5):523-35. doi: 10.1016/0049-3848(94)90273-9. Thromb Res. 1994. PMID: 8085253
SC-49992, a mimetic of the peptide arginine-glycine-aspartic acid-phenylalanine that blocks platelet aggregation, enhances recombinant tissue plasminogen activator-induced thrombolysis and prevents reocclusion in a canine model of coronary artery thrombosis.
Feigen LP, Nicholson NS, King LW, Campion JG, Tjoeng FS, Panzer-Knodle SG. Feigen LP, et al. Among authors: panzer knodle sg. J Pharmacol Exp Ther. 1993 Dec;267(3):1191-7. J Pharmacol Exp Ther. 1993. PMID: 8263779
Potent in vitro and in vivo inhibitors of platelet aggregation based upon the Arg-Gly-Asp-Phe sequence of fibrinogen. A proposal on the nature of the binding interaction between the Arg-guanidine of RGDX mimetics and the platelet GP IIb-IIIa receptor.
Zablocki JA, Miyano M, Garland RB, Pireh D, Schretzman L, Rao SN, Lindmark RJ, Panzer-Knodle SG, Nicholson NS, Taite BB, et al. Zablocki JA, et al. Among authors: panzer knodle sg. J Med Chem. 1993 Jun 25;36(13):1811-9. doi: 10.1021/jm00065a003. J Med Chem. 1993. PMID: 8515420
Administration of a small molecule tissue factor/factor VIIa inhibitor in a non-human primate thrombosis model of venous thrombosis: effects on thrombus formation and bleeding time.
Szalony JA, Suleymanov OD, Salyers AK, Panzer-Knodle SG, Blom JD, LaChance RM, Case BL, Parlow JJ, South MS, Wood RS, Nicholson NS. Szalony JA, et al. Among authors: panzer knodle sg. Thromb Res. 2003;112(3):167-74. doi: 10.1016/j.thromres.2003.10.017. Thromb Res. 2003. PMID: 14967414
SC-54684A: an orally active inhibitor of platelet aggregation.
Nicholson NS, Panzer-Knodle SG, Salyers AK, Taite BB, Szalony JA, Haas NF, King LW, Zablocki JA, Keller BT, Broschat K, et al. Nicholson NS, et al. Among authors: panzer knodle sg. Circulation. 1995 Jan 15;91(2):403-10. doi: 10.1161/01.cir.91.2.403. Circulation. 1995. PMID: 7805244
Assessment of platelet function assays.
Nicholson NS, Panzer-Knodle SG, Haas NF, Taite BB, Szalony JA, Page JD, Feigen LP, Lansky DM, Salyers AK. Nicholson NS, et al. Among authors: panzer knodle sg. Am Heart J. 1998 May;135(5 Pt 2 Su):S170-8. doi: 10.1016/s0002-8703(98)70245-5. Am Heart J. 1998. PMID: 9588396 Review.
16 results