Mirkin BL - Search Results

1

Cathepsin L inhibition suppresses drug resistance in vitro and in vivo: a putative mechanism.

Zheng X, Chu F, Chou PM, Gallati C, Dier U, Mirkin BL, Mousa SA, Rebbaa A. Zheng X, et al. Among authors: mirkin bl. Am J Physiol Cell Physiol. 2009 Jan;296(1):C65-74. doi: 10.1152/ajpcell.00082.2008. Epub 2008 Oct 29. Am J Physiol Cell Physiol. 2009. PMID: 18971393 Free PMC article.

2

Caspase inhibition switches doxorubicin-induced apoptosis to senescence.

Rebbaa A, Zheng X, Chou PM, Mirkin BL. Rebbaa A, et al. Among authors: mirkin bl. Oncogene. 2003 May 8;22(18):2805-11. doi: 10.1038/sj.onc.1206366. Oncogene. 2003. PMID: 12743603

3

Senescence-initiated reversal of drug resistance: specific role of cathepsin L.

Zheng X, Chou PM, Mirkin BL, Rebbaa A. Zheng X, et al. Among authors: mirkin bl. Cancer Res. 2004 Mar 1;64(5):1773-80. doi: 10.1158/0008-5472.can-03-0820. Cancer Res. 2004. PMID: 14996739

4

Identification of midkine as a mediator for intercellular transfer of drug resistance.

Mirkin BL, Clark S, Zheng X, Chu F, White BD, Greene M, Rebbaa A. Mirkin BL, et al. Oncogene. 2005 Jul 21;24(31):4965-74. doi: 10.1038/sj.onc.1208671. Oncogene. 2005. PMID: 15897897

5

Control of multidrug resistance gene mdr1 and cancer resistance to chemotherapy by the longevity gene sirt1.

Chu F, Chou PM, Zheng X, Mirkin BL, Rebbaa A. Chu F, et al. Among authors: mirkin bl. Cancer Res. 2005 Nov 15;65(22):10183-7. doi: 10.1158/0008-5472.CAN-05-2002. Cancer Res. 2005. PMID: 16288004

6

Cellular conditioning with trichostatin A enhances the anti-stress response through up-regulation of HDAC4 and down-regulation of the IGF/Akt pathway.

Chu F, Chou P, Mirkin BL, Mousa SA, Rebbaa A. Chu F, et al. Among authors: mirkin bl. Aging Cell. 2008 Aug;7(4):516-25. doi: 10.1111/j.1474-9726.2008.00403.x. Epub 2008 Jul 8. Aging Cell. 2008. PMID: 18489729 Free PMC article.

7

Role of the proteolytic hierarchy between cathepsin L, cathepsin D and caspase-3 in regulation of cellular susceptibility to apoptosis and autophagy.

Zheng X, Chu F, Mirkin BL, Sudha T, Mousa SA, Rebbaa A. Zheng X, et al. Among authors: mirkin bl. Biochim Biophys Acta. 2008 Dec;1783(12):2294-300. doi: 10.1016/j.bbamcr.2008.07.027. Epub 2008 Aug 13. Biochim Biophys Acta. 2008. PMID: 18775751 Free article.

8

Doxorubicin resistant neuroblastoma cells secrete factors that activate AKT and attenuate cytotoxicity in drug-sensitive cells.

Emran MA, Rebbaa A, Mirkin BL. Emran MA, et al. Among authors: mirkin bl. Cancer Lett. 2002 Aug 8;182(1):53-9. doi: 10.1016/s0304-3835(02)00062-9. Cancer Lett. 2002. PMID: 12175523

9

Doxorubicin-induced apoptosis in caspase-8-deficient neuroblastoma cells is mediated through direct action on mitochondria.

Rebbaa A, Chou PM, Emran M, Mirkin BL. Rebbaa A, et al. Among authors: mirkin bl. Cancer Chemother Pharmacol. 2001 Dec;48(6):423-8. doi: 10.1007/s002800100375. Cancer Chemother Pharmacol. 2001. PMID: 11800021

10

The role of histone acetylation versus DNA damage in drug-induced senescence and apoptosis.

Rebbaa A, Zheng X, Chu F, Mirkin BL. Rebbaa A, et al. Among authors: mirkin bl. Cell Death Differ. 2006 Nov;13(11):1960-7. doi: 10.1038/sj.cdd.4401895. Epub 2006 Mar 24. Cell Death Differ. 2006. PMID: 16557274

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