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Nitro-oleic acid, a novel and irreversible inhibitor of xanthine oxidoreductase.
Kelley EE, Batthyany CI, Hundley NJ, Woodcock SR, Bonacci G, Del Rio JM, Schopfer FJ, Lancaster JR Jr, Freeman BA, Tarpey MM. Kelley EE, et al. Among authors: tarpey mm. J Biol Chem. 2008 Dec 26;283(52):36176-84. doi: 10.1074/jbc.M802402200. Epub 2008 Oct 29. J Biol Chem. 2008. PMID: 18974051 Free PMC article.
Hydrogen peroxide is the major oxidant product of xanthine oxidase.
Kelley EE, Khoo NK, Hundley NJ, Malik UZ, Freeman BA, Tarpey MM. Kelley EE, et al. Among authors: tarpey mm. Free Radic Biol Med. 2010 Feb 15;48(4):493-8. doi: 10.1016/j.freeradbiomed.2009.11.012. Epub 2009 Nov 24. Free Radic Biol Med. 2010. PMID: 19941951 Free PMC article.
Xanthine Oxidoreductase Function Contributes to Normal Wound Healing.
Madigan MC, McEnaney RM, Shukla AJ, Hong G, Kelley EE, Tarpey MM, Gladwin M, Zuckerbraun BS, Tzeng E. Madigan MC, et al. Among authors: tarpey mm. Mol Med. 2015 Apr 14;21(1):313-22. doi: 10.2119/molmed.2014.00191. Mol Med. 2015. PMID: 25879627 Free PMC article.
36 results