Newton DJ - Search Results

1

Site-directed mutagenesis of glutathione S-transferase YaYa: nonessential role of histidine in catalysis.

Wang RW, Newton DJ, Pickett CB, Lu AY. Wang RW, et al. Among authors: newton dj. Arch Biochem Biophys. 1991 May 1;286(2):574-8. doi: 10.1016/0003-9861(91)90082-t. Arch Biochem Biophys. 1991. PMID: 1897979

2

Site-directed mutagenesis of glutathione S-transferase YaYa. Important roles of tyrosine 9 and aspartic acid 101 in catalysis.

Wang RW, Newton DJ, Huskey SE, McKeever BM, Pickett CB, Lu AY. Wang RW, et al. Among authors: newton dj. J Biol Chem. 1992 Oct 5;267(28):19866-71. J Biol Chem. 1992. PMID: 1400302 Free article.

3

Site-directed mutagenesis of glutathione S-transferase YaYa: functional studies of histidine, cysteine, and tryptophan mutants.

Wang RW, Newton DJ, Pickett CB, Lu AY. Wang RW, et al. Among authors: newton dj. Arch Biochem Biophys. 1992 Aug 15;297(1):86-91. doi: 10.1016/0003-9861(92)90644-c. Arch Biochem Biophys. 1992. PMID: 1637185

4

Site-directed mutagenesis of glutathione S-transferase YaYa. Mapping the glutathione-binding site.

Wang RW, Newton DJ, Johnson AR, Pickett CB, Lu AY. Wang RW, et al. Among authors: newton dj. J Biol Chem. 1993 Nov 15;268(32):23981-5. J Biol Chem. 1993. PMID: 8226940 Free article.

5

Fluorescence characterization of Trp 21 in rat glutathione S-transferase 1-1: microconformational changes induced by S-hexyl glutathione.

Wang RW, Bird AW, Newton DJ, Lu AY, Atkins WM. Wang RW, et al. Among authors: newton dj. Protein Sci. 1993 Dec;2(12):2085-94. doi: 10.1002/pro.5560021209. Protein Sci. 1993. PMID: 8298458 Free PMC article.

6

Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.

Newton DJ, Wang RW, Lu AY. Newton DJ, et al. Drug Metab Dispos. 1995 Jan;23(1):154-8. Drug Metab Dispos. 1995. PMID: 7720520

7

The catalytic mechanism of glutathione S-transferase (GST). Spectroscopic determination of the pKa of Tyr-9 in rat alpha 1-1 GST.

Atkins WM, Wang RW, Bird AW, Newton DJ, Lu AY. Atkins WM, et al. Among authors: newton dj. J Biol Chem. 1993 Sep 15;268(26):19188-91. J Biol Chem. 1993. PMID: 8366071 Free article.

8

Human cytochrome P450 3A4-catalyzed testosterone 6 beta-hydroxylation and erythromycin N-demethylation. Competition during catalysis.

Wang RW, Newton DJ, Scheri TD, Lu AY. Wang RW, et al. Among authors: newton dj. Drug Metab Dispos. 1997 Apr;25(4):502-7. Drug Metab Dispos. 1997. PMID: 9107550

9

Inhibitory anti-CYP3A4 peptide antibody: mapping of inhibitory epitope and specificity toward other CYP3A isoforms.

Wang RW, Newton DJ, Liu NY, Shou M, Rushmore T, Lu AY. Wang RW, et al. Among authors: newton dj. Drug Metab Dispos. 1999 Feb;27(2):167-72. Drug Metab Dispos. 1999. PMID: 9929498

10

FK 506 metabolism in human liver microsomes: investigation of the involvement of cytochrome P450 isozymes other than CYP3A4.

Karanam BV, Vincent SH, Newton DJ, Wang RW, Chiu SH. Karanam BV, et al. Among authors: newton dj. Drug Metab Dispos. 1994 Sep-Oct;22(5):811-4. Drug Metab Dispos. 1994. PMID: 7530623 No abstract available.

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