Sechi M - Search Results

1

From ligand to complexes. Part 2. Remarks on human immunodeficiency virus type 1 integrase inhibition by beta-diketo acid metal complexes.

Bacchi A, Biemmi M, Carcelli M, Carta F, Compari C, Fisicaro E, Rogolino D, Sechi M, Sippel M, Sotriffer CA, Sanchez TW, Neamati N. Bacchi A, et al. Among authors: sechi m. J Med Chem. 2008 Nov 27;51(22):7253-64. doi: 10.1021/jm800893q. J Med Chem. 2008. PMID: 18983138

2

Design and synthesis of novel dihydroxyindole-2-carboxylic acids as HIV-1 integrase inhibitors.

Sechi M, Angotzi G, Dallocchio R, Dessì A, Carta F, Sannia L, Mariani A, Fiori S, Sanchez T, Movsessian L, Plasencia C, Neamati N. Sechi M, et al. Antivir Chem Chemother. 2004 Mar;15(2):67-81. doi: 10.1177/095632020401500203. Antivir Chem Chemother. 2004. PMID: 15185725 Free article.

3

Design and synthesis of novel indole beta-diketo acid derivatives as HIV-1 integrase inhibitors.

Sechi M, Derudas M, Dallocchio R, Dessì A, Bacchi A, Sannia L, Carta F, Palomba M, Ragab O, Chan C, Shoemaker R, Sei S, Dayam R, Neamati N. Sechi M, et al. J Med Chem. 2004 Oct 7;47(21):5298-310. doi: 10.1021/jm049944f. J Med Chem. 2004. PMID: 15456274

4

Design of novel bioisosteres of beta-diketo acid inhibitors of HIV-1 integrase.

Sechi M, Sannia L, Carta F, Palomba M, Dallocchio R, Dessì A, Derudas M, Zawahir Z, Neamati N. Sechi M, et al. Antivir Chem Chemother. 2005;16(1):41-61. doi: 10.1177/095632020501600105. Antivir Chem Chemother. 2005. PMID: 15739621 Free article.

5

From ligand to complexes: inhibition of human immunodeficiency virus type 1 integrase by beta-diketo acid metal complexes.

Sechi M, Bacchi A, Carcelli M, Compari C, Duce E, Fisicaro E, Rogolino D, Gates P, Derudas M, Al-Mawsawi LQ, Neamati N. Sechi M, et al. J Med Chem. 2006 Jul 13;49(14):4248-60. doi: 10.1021/jm060193m. J Med Chem. 2006. PMID: 16821784

6

Single amino acid substitution in HIV-1 integrase catalytic core causes a dramatic shift in inhibitor selectivity.

Al-Mawsawi LQ, Sechi M, Neamati N. Al-Mawsawi LQ, et al. Among authors: sechi m. FEBS Lett. 2007 Mar 20;581(6):1151-6. doi: 10.1016/j.febslet.2007.02.023. Epub 2007 Feb 20. FEBS Lett. 2007. PMID: 17328897 Free article.

7

Design and synthesis of bis-amide and hydrazide-containing derivatives of malonic acid as potential HIV-1 integrase inhibitors.

Sechi M, Azzena U, Delussu MP, Dallocchio R, Dessì A, Cosseddu A, Pala N, Neamati N. Sechi M, et al. Molecules. 2008 Oct 1;13(10):2442-61. doi: 10.3390/molecules13102442. Molecules. 2008. PMID: 18830166 Free PMC article.

8

Design and synthesis of novel dihydroquinoline-3-carboxylic acids as HIV-1 integrase inhibitors.

Sechi M, Rizzi G, Bacchi A, Carcelli M, Rogolino D, Pala N, Sanchez TW, Taheri L, Dayam R, Neamati N. Sechi M, et al. Bioorg Med Chem. 2009 Apr 1;17(7):2925-35. doi: 10.1016/j.bmc.2008.10.088. Epub 2008 Nov 6. Bioorg Med Chem. 2009. PMID: 19026554

9

Design, synthesis, molecular modeling, and anti-HIV-1 integrase activity of a series of photoactivatable diketo acid-containing inhibitors as affinity probes.

Sechi M, Carta F, Sannia L, Dallocchio R, Dessì A, Al-Safi RI, Neamati N. Sechi M, et al. Antiviral Res. 2009 Mar;81(3):267-76. doi: 10.1016/j.antiviral.2008.12.010. Epub 2009 Jan 9. Antiviral Res. 2009. PMID: 19135482

10

HIV-1 IN strand transfer chelating inhibitors: a focus on metal binding.

Bacchi A, Carcelli M, Compari C, Fisicaro E, Pala N, Rispoli G, Rogolino D, Sanchez TW, Sechi M, Neamati N. Bacchi A, et al. Among authors: sechi m. Mol Pharm. 2011 Apr 4;8(2):507-19. doi: 10.1021/mp100343x. Epub 2011 Mar 8. Mol Pharm. 2011. PMID: 21323359

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