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Page 1
Signalling inhibitors against Mycobacterium tuberculosis--early days of a new therapeutic concept in tuberculosis.
Hegymegi-Barakonyi B, Székely R, Varga Z, Kiss R, Borbély G, Németh G, Bánhegyi P, Pató J, Greff Z, Horváth Z, Mészáros G, Marosfalvi J, Erōs D, Szántai-Kis C, Breza N, Garavaglia S, Perozzi S, Rizzi M, Hafenbradl D, Ko M, Av-Gay Y, Klebl BM, Orfi L, Kéri G. Hegymegi-Barakonyi B, et al. Among authors: klebl bm. Curr Med Chem. 2008;15(26):2760-70. doi: 10.2174/092986708786242886. Curr Med Chem. 2008. PMID: 18991635
Drug discovery in the kinase inhibitory field using the Nested Chemical Library technology.
Kéri G, Székelyhidi Z, Bánhegyi P, Varga Z, Hegymegi-Barakonyi B, Szántai-Kis C, Hafenbradl D, Klebl B, Muller G, Ullrich A, Erös D, Horváth Z, Greff Z, Marosfalvi J, Pató J, Szabadkai I, Szilágyi I, Szegedi Z, Varga I, Wáczek F, Orfi L. Kéri G, et al. Assay Drug Dev Technol. 2005 Oct;3(5):543-51. doi: 10.1089/adt.2005.3.543. Assay Drug Dev Technol. 2005. PMID: 16305311 Review.
Synthesis of selective SRPK-1 inhibitors: novel tricyclic quinoxaline derivatives.
Székelyhidi Z, Pató J, Wáczek F, Bánhegyi P, Hegymegi-Barakonyi B, Erös D, Mészáros G, Hollósy F, Hafenbradl D, Obert S, Klebl B, Kéri G, Orfi L. Székelyhidi Z, et al. Bioorg Med Chem Lett. 2005 Jul 1;15(13):3241-6. doi: 10.1016/j.bmcl.2005.04.064. Bioorg Med Chem Lett. 2005. PMID: 15925511
Systematic Kinase Inhibitor Profiling Identifies CDK9 as a Synthetic Lethal Target in NUT Midline Carcinoma.
Brägelmann J, Dammert MA, Dietlein F, Heuckmann JM, Choidas A, Böhm S, Richters A, Basu D, Tischler V, Lorenz C, Habenberger P, Fang Z, Ortiz-Cuaran S, Leenders F, Eickhoff J, Koch U, Getlik M, Termathe M, Sallouh M, Greff Z, Varga Z, Balke-Want H, French CA, Peifer M, Reinhardt HC, Örfi L, Kéri G, Ansén S, Heukamp LC, Büttner R, Rauh D, Klebl BM, Thomas RK, Sos ML. Brägelmann J, et al. Among authors: klebl bm. Cell Rep. 2017 Sep 19;20(12):2833-2845. doi: 10.1016/j.celrep.2017.08.082. Cell Rep. 2017. PMID: 28930680 Free PMC article.
Cellular targets of gefitinib.
Brehmer D, Greff Z, Godl K, Blencke S, Kurtenbach A, Weber M, Müller S, Klebl B, Cotten M, Kéri G, Wissing J, Daub H. Brehmer D, et al. Cancer Res. 2005 Jan 15;65(2):379-82. Cancer Res. 2005. PMID: 15695376
Kinase Chemodiversity from the Arctic: The Breitfussins.
Hansen KØ, Andersen JH, Bayer A, Pandey SK, Lorentzen M, Jørgensen KB, Sydnes MO, Guttormsen Y, Baumann M, Koch U, Klebl B, Eickhoff J, Haug BE, Isaksson J, Hansen EH. Hansen KØ, et al. J Med Chem. 2019 Nov 27;62(22):10167-10181. doi: 10.1021/acs.jmedchem.9b01006. Epub 2019 Nov 14. J Med Chem. 2019. PMID: 31647655
Insight into Targeting Exon20 Insertion Mutations of the Epidermal Growth Factor Receptor with Wild Type-Sparing Inhibitors.
Lategahn J, Tumbrink HL, Schultz-Fademrecht C, Heimsoeth A, Werr L, Niggenaber J, Keul M, Parmaksiz F, Baumann M, Menninger S, Zent E, Landel I, Weisner J, Jeyakumar K, Heyden L, Russ N, Müller F, Lorenz C, Brägelmann J, Spille I, Grabe T, Müller MP, Heuckmann JM, Klebl BM, Nussbaumer P, Sos ML, Rauh D. Lategahn J, et al. Among authors: klebl bm. J Med Chem. 2022 May 12;65(9):6643-6655. doi: 10.1021/acs.jmedchem.1c02080. Epub 2022 Apr 29. J Med Chem. 2022. PMID: 35486541
59 results