Wang S - Search Results

1

Noonan syndrome/leukemia-associated gain-of-function mutations in SHP-2 phosphatase (PTPN11) enhance cell migration and angiogenesis.

Wang S, Yu WM, Zhang W, McCrae KR, Neel BG, Qu CK. Wang S, et al. J Biol Chem. 2009 Jan 9;284(2):913-20. doi: 10.1074/jbc.M804129200. Epub 2008 Nov 13. J Biol Chem. 2009. PMID: 19008228 Free PMC article.

2

A germline gain-of-function mutation in Ptpn11 (Shp-2) phosphatase induces myeloproliferative disease by aberrant activation of hematopoietic stem cells.

Xu D, Wang S, Yu WM, Chan G, Araki T, Bunting KD, Neel BG, Qu CK. Xu D, et al. Among authors: wang s. Blood. 2010 Nov 4;116(18):3611-21. doi: 10.1182/blood-2010-01-265652. Epub 2010 Jul 22. Blood. 2010. PMID: 20651068 Free PMC article.

3

Gain-of-function mutations of Ptpn11 (Shp2) cause aberrant mitosis and increase susceptibility to DNA damage-induced malignancies.

Liu X, Zheng H, Li X, Wang S, Meyerson HJ, Yang W, Neel BG, Qu CK. Liu X, et al. Among authors: wang s. Proc Natl Acad Sci U S A. 2016 Jan 26;113(4):984-9. doi: 10.1073/pnas.1508535113. Epub 2016 Jan 11. Proc Natl Acad Sci U S A. 2016. PMID: 26755576 Free PMC article.

4

Abnormal Th1 cell differentiation and IFN-gamma production in T lymphocytes from motheaten viable mice mutant for Src homology 2 domain-containing protein tyrosine phosphatase-1.

Yu WM, Wang S, Keegan AD, Williams MS, Qu CK. Yu WM, et al. Among authors: wang s. J Immunol. 2005 Jan 15;174(2):1013-9. doi: 10.4049/jimmunol.174.2.1013. J Immunol. 2005. PMID: 15634925

5

A tyrosine phosphatase SHP2 gain-of-function mutation enhances malignancy of breast carcinoma.

Hu Z, Wang X, Fang H, Liu Y, Chen D, Zhang Q, Liu X, Wei D, Qu C, Wang S. Hu Z, et al. Among authors: wang x, wang s. Oncotarget. 2016 Feb 2;7(5):5664-76. doi: 10.18632/oncotarget.6561. Oncotarget. 2016. PMID: 26673822 Free PMC article.

6

Rapid induction and activation of Tec tyrosine kinase in liver regeneration.

Wang SY, Li FF, Zheng H, Yu KK, Ni F, Yang XM, Qu CK, Li J. Wang SY, et al. J Gastroenterol Hepatol. 2006 Apr;21(4):668-73. doi: 10.1111/j.1440-1746.2006.04259.x. J Gastroenterol Hepatol. 2006. PMID: 16677151

7

SHP2 Inhibition Benefits Epidermal Growth Factor Receptor-mutated Non-Small Cell Lung Cancer Therapy.

Xia L, Wen L, Wang S. Xia L, et al. Among authors: wang s. Mini Rev Med Chem. 2021;21(11):1314-1321. doi: 10.2174/1389557520666201127104104. Mini Rev Med Chem. 2021. PMID: 33245269 Review.

8

Overexpression of SHP2 tyrosine phosphatase promotes the tumorigenesis of breast carcinoma.

Hu Z, Fang H, Wang X, Chen D, Chen Z, Wang S. Hu Z, et al. Among authors: wang x, wang s. Oncol Rep. 2014 Jul;32(1):205-12. doi: 10.3892/or.2014.3201. Epub 2014 May 20. Oncol Rep. 2014. PMID: 24858400

9

The gain-of-function mutation E76K in SHP2 promotes CAC tumorigenesis and induces EMT via the Wnt/β-catenin signaling pathway.

Zhang Q, Li Y, Zhao R, Wang X, Fan C, Xu Y, Liu Y, Li J, Wang S. Zhang Q, et al. Among authors: wang x, wang s. Mol Carcinog. 2018 May;57(5):619-628. doi: 10.1002/mc.22785. Epub 2018 Feb 8. Mol Carcinog. 2018. PMID: 29323748

10

Ethanol promotes mammary tumor growth and angiogenesis: the involvement of chemoattractant factor MCP-1.

Wang S, Xu M, Li F, Wang X, Bower KA, Frank JA, Lu Y, Chen G, Zhang Z, Ke Z, Shi X, Luo J. Wang S, et al. Among authors: wang x. Breast Cancer Res Treat. 2012 Jun;133(3):1037-48. doi: 10.1007/s10549-011-1902-7. Epub 2011 Dec 9. Breast Cancer Res Treat. 2012. PMID: 22160640 Free PMC article.

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