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The beta-lactam antibiotic, ceftriaxone, dramatically improves survival, increases glutamate uptake and induces neurotrophins in stroke.
Thöne-Reineke C, Neumann C, Namsolleck P, Schmerbach K, Krikov M, Schefe JH, Lucht K, Hörtnagl H, Godes M, Müller S, Rumschüssel K, Funke-Kaiser H, Villringer A, Steckelings UM, Unger T. Thöne-Reineke C, et al. Among authors: schefe jh. J Hypertens. 2008 Dec;26(12):2426-35. doi: 10.1097/HJH.0b013e328313e403. J Hypertens. 2008. PMID: 19008722
The promyelocytic leukemia zinc finger (PLZF) protein exerts neuroprotective effects in neuronal cells and is dysregulated in experimental stroke.
Seidel K, Kirsch S, Lucht K, Zaade D, Reinemund J, Schmitz J, Klare S, Li Y, Schefe JH, Schmerbach K, Goldin-Lang P, Zollmann FS, Thöne-Reineke C, Unger T, Funke-Kaiser H. Seidel K, et al. Among authors: schefe jh. Brain Pathol. 2011 Jan;21(1):31-43. doi: 10.1111/j.1750-3639.2010.00427.x. Brain Pathol. 2011. PMID: 20731660 Free PMC article.
PLZF and the (pro)renin receptor.
Schefe JH, Unger T, Funke-Kaiser H. Schefe JH, et al. J Mol Med (Berl). 2008 Jun;86(6):623-7. doi: 10.1007/s00109-008-0320-8. Epub 2008 Mar 12. J Mol Med (Berl). 2008. PMID: 18335187 Review.
Poly(ADP-ribose) polymerase-1 (PARP-1) transcriptionally regulates angiotensin AT2 receptor (AT2R) and AT2R binding protein (ATBP) genes.
Reinemund J, Seidel K, Steckelings UM, Zaade D, Klare S, Rompe F, Katerbaum M, Schacherl J, Li Y, Menk M, Schefe JH, Goldin-Lang P, Szabo C, Olah G, Unger T, Funke-Kaiser H. Reinemund J, et al. Among authors: schefe jh. Biochem Pharmacol. 2009 Jun 15;77(12):1795-805. doi: 10.1016/j.bcp.2009.02.025. Epub 2009 Mar 19. Biochem Pharmacol. 2009. PMID: 19344625 Free article.
17 results