Rackelmann N - Search Results

1

Application of secondary alkyl halides to a domino aryl alkylation reaction for the synthesis of aromatic heterocycles.

Rudolph A, Rackelmann N, Turcotte-Savard MO, Lautens M. Rudolph A, et al. Among authors: rackelmann n. J Org Chem. 2009 Jan 2;74(1):289-97. doi: 10.1021/jo802180h. J Org Chem. 2009. PMID: 19012432

2

Stereochemical and mechanistic investigations of a palladium-catalyzed annulation of secondary alkyl iodides.

Rudolph A, Rackelmann N, Lautens M. Rudolph A, et al. Among authors: rackelmann n. Angew Chem Int Ed Engl. 2007;46(9):1485-8. doi: 10.1002/anie.200603888. Angew Chem Int Ed Engl. 2007. PMID: 17221898 No abstract available.

3

Enantioselective total syntheses of the Ipecacuanha alkaloid emetine, the Alangium alkaloid tubulosine and a novel benzoquinolizidine alkaloid by using a domino process.

Tietze LF, Rackelmann N, Müller I. Tietze LF, et al. Among authors: rackelmann n. Chemistry. 2004 Jun 7;10(11):2722-31. doi: 10.1002/chem.200306039. Chemistry. 2004. PMID: 15195303

4

Catalyst-controlled stereoselective combinatorial synthesis.

Tietze LF, Rackelmann N, Sekar G. Tietze LF, et al. Among authors: rackelmann n. Angew Chem Int Ed Engl. 2003 Sep 15;42(35):4254-7. doi: 10.1002/anie.200351129. Angew Chem Int Ed Engl. 2003. PMID: 14502750 No abstract available.

5

SAR340835, a Novel Selective Na⁺/Ca²⁺ Exchanger Inhibitor, Improves Cardiac Function and Restores Sympathovagal Balance in Heart Failure.

Pelat M, Barbe F, Daveu C, Ly-Nguyen L, Lartigue T, Marque S, Tavares G, Ballet V, Guillon JM, Steinmeyer K, Wirth K, Gögelein H, Arndt P, Rackelmann N, Weston J, Bellevergue P, McCort G, Trellu M, Lucats L, Beauverger P, Pruniaux-Harnist MP, Janiak P, Chézalviel-Guilbert F. Pelat M, et al. Among authors: rackelmann n. J Pharmacol Exp Ther. 2021 May;377(2):293-304. doi: 10.1124/jpet.120.000238. Epub 2021 Feb 18. J Pharmacol Exp Ther. 2021. PMID: 33602875

6

Photoredox-Mediated Hydrogen Isotope Exchange Reactions of Amino-Acids, Peptides, and Peptide-Derived Drugs.

Legros F, Fernandez-Rodriguez P, Mishra A, Weck R, Bauer A, Sandvoss M, Ruf S, Méndez M, Mora-Radó H, Rackelmann N, Pöverlein C, Derdau V. Legros F, et al. Among authors: rackelmann n. Chemistry. 2020 Oct 6;26(56):12738-12742. doi: 10.1002/chem.202003464. Epub 2020 Sep 16. Chemistry. 2020. PMID: 32716576

7

Design, Synthesis, and Pharmacological Evaluation of Potent Positive Allosteric Modulators of the Glucagon-like Peptide-1 Receptor (GLP-1R).

Méndez M, Matter H, Defossa E, Kurz M, Lebreton S, Li Z, Lohmann M, Löhn M, Mors H, Podeschwa M, Rackelmann N, Riedel J, Safar P, Thorpe DS, Schäfer M, Weitz D, Breitschopf K. Méndez M, et al. Among authors: rackelmann n. J Med Chem. 2020 Mar 12;63(5):2292-2307. doi: 10.1021/acs.jmedchem.9b01071. Epub 2019 Oct 23. J Med Chem. 2020. PMID: 31596080

8

Discovery and Optimization of 1-Phenoxy-2-aminoindanes as Potent, Selective, and Orally Bioavailable Inhibitors of the Na⁺/H⁺ Exchanger Type 3 (NHE3).

Rackelmann N, Matter H, Englert H, Follmann M, Maier T, Weston J, Arndt P, Heyse W, Mertsch K, Wirth K, Bialy L. Rackelmann N, et al. J Med Chem. 2016 Oct 13;59(19):8812-8829. doi: 10.1021/acs.jmedchem.6b00624. Epub 2016 Sep 22. J Med Chem. 2016. PMID: 27606885

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