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Bacterial artificial chromosome transgenic mice expressing a truncated mutant parkin exhibit age-dependent hypokinetic motor deficits, dopaminergic neuron degeneration, and accumulation of proteinase K-resistant alpha-synuclein.
Lu XH, Fleming SM, Meurers B, Ackerson LC, Mortazavi F, Lo V, Hernandez D, Sulzer D, Jackson GR, Maidment NT, Chesselet MF, Yang XW. Lu XH, et al. J Neurosci. 2009 Feb 18;29(7):1962-76. doi: 10.1523/JNEUROSCI.5351-08.2009. J Neurosci. 2009. PMID: 19228951 Free PMC article.
Nuclei and subnuclei gene expression profiling in mammalian brain.
Bonaventure P, Guo H, Tian B, Liu X, Bittner A, Roland B, Salunga R, Ma XJ, Kamme F, Meurers B, Bakker M, Jurzak M, Leysen JE, Erlander MG. Bonaventure P, et al. Brain Res. 2002 Jul 5;943(1):38-47. doi: 10.1016/s0006-8993(02)02504-0. Brain Res. 2002. PMID: 12088837
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