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A pilot trial of the microtubule-interacting peptide (NAP) in mice overexpressing alpha-synuclein shows improvement in motor function and reduction of alpha-synuclein inclusions.
Fleming SM, Mulligan CK, Richter F, Mortazavi F, Lemesre V, Frias C, Zhu C, Stewart A, Gozes I, Morimoto B, Chesselet MF. Fleming SM, et al. Among authors: richter f. Mol Cell Neurosci. 2011 Mar;46(3):597-606. doi: 10.1016/j.mcn.2010.12.011. Epub 2010 Dec 27. Mol Cell Neurosci. 2011. PMID: 21193046 Free PMC article.
Elevated tonic extracellular dopamine concentration and altered dopamine modulation of synaptic activity precede dopamine loss in the striatum of mice overexpressing human α-synuclein.
Lam HA, Wu N, Cely I, Kelly RL, Hean S, Richter F, Magen I, Cepeda C, Ackerson LC, Walwyn W, Masliah E, Chesselet MF, Levine MS, Maidment NT. Lam HA, et al. Among authors: richter f. J Neurosci Res. 2011 Jul;89(7):1091-102. doi: 10.1002/jnr.22611. Epub 2011 Apr 12. J Neurosci Res. 2011. PMID: 21488084 Free PMC article.
Modelling of Parkinson's disease in mice.
Chesselet MF, Richter F. Chesselet MF, et al. Among authors: richter f. Lancet Neurol. 2011 Dec;10(12):1108-18. doi: 10.1016/S1474-4422(11)70227-7. Lancet Neurol. 2011. PMID: 22094131 Review.
561 results