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New ifosfamide analogs designed for lower associated neurotoxicity and nephrotoxicity with modified alkylating kinetics leading to enhanced in vitro anticancer activity.
Storme T, Deroussent A, Mercier L, Prost E, Re M, Munier F, Martens T, Bourget P, Vassal G, Royer J, Paci A. Storme T, et al. Among authors: vassal g. J Pharmacol Exp Ther. 2009 Feb;328(2):598-609. doi: 10.1124/jpet.108.144170. Epub 2008 Nov 18. J Pharmacol Exp Ther. 2009. PMID: 19017849
Metabolism of irinotecan (CPT-11) by CYP3A4 and CYP3A5 in humans.
Santos A, Zanetta S, Cresteil T, Deroussent A, Pein F, Raymond E, Vernillet L, Risse ML, Boige V, Gouyette A, Vassal G. Santos A, et al. Among authors: vassal g. Clin Cancer Res. 2000 May;6(5):2012-20. Clin Cancer Res. 2000. PMID: 10815927 Clinical Trial.
Liquid chromatography-mass spectrometry assay for quantitation of ifosfamide and its N-deschloroethylated metabolites in rat microsomal medium.
Storme T, Mercier L, Deroussent A, Re M, Martens T, Royer J, Bourget P, Vassal G, Paci A. Storme T, et al. Among authors: vassal g. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Jun 25;820(2):251-9. doi: 10.1016/j.jchromb.2005.03.023. Epub 2005 Apr 25. J Chromatogr B Analyt Technol Biomed Life Sci. 2005. PMID: 15899378
344 results