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An ultra-early, transient interferon-associated innate immune response associates with protection from SARS-CoV-2 infection despite exposure.
Fenn J, Madon K, Conibear E, Derelle R, Nevin S, Kundu R, Hakki S, Tregoning JS, Koycheva A, Derqui N, Tolosa-Wright M, Jonnerby J, Wang L, Baldwin S, Pillay TD, Thwaites RS, Luca C, Varro R, Badhan A, Parker E, Rosadas C, McClure M, Tedder R, Taylor G, Lalvani A; INSTINCT Study Investigators. Fenn J, et al. Among authors: badhan a. EBioMedicine. 2025 Jan;111:105475. doi: 10.1016/j.ebiom.2024.105475. Epub 2024 Dec 11. EBioMedicine. 2025. PMID: 39667271 Free PMC article.
Rapid emergence of transmissible SARS-CoV-2 variants in mild community cases.
Crone MA, Hakki S, Fenn J, Zhou J, Oliveira CRd, Madon KJ, Koycheva A, Badhan A, Jonnerby J, Nevin S, Conibear E, Derelle R, Varro R, Luca C, Ahmad S, Zambon M, Barclay WS, Dunning J, Freemont PS, Taylor GP, Lalvani A. Crone MA, et al. Among authors: badhan a. Microbiol Spectr. 2024 Apr 2;12(4):e0363423. doi: 10.1128/spectrum.03634-23. Epub 2024 Mar 14. Microbiol Spectr. 2024. PMID: 38483161 Free PMC article. No abstract available.
A pro-inflammatory gut mucosal cytokine response is associated with mild COVID-19 disease and superior induction of serum antibodies.
Costigan D, Fenn J, Yen S, Ilott N, Bullers S, Hale J, Greenhalf W, Conibear E, Koycheva A, Madon K, Jahan I, Huang M, Badhan A, Parker E, Rosadas C, Jones K, McClure M, Tedder R, Taylor G, Baillie KJ, Semple MG, Openshaw PJM, Pearson C, Johnson J; INSTINCT Study Group; ISARIC4C investigators; Lalvani A, Thornton EE. Costigan D, et al. Among authors: badhan a. Mucosal Immunol. 2024 Feb;17(1):111-123. doi: 10.1016/j.mucimm.2023.11.005. Epub 2023 Nov 22. Mucosal Immunol. 2024. PMID: 37995912 Free PMC article.
Multiplexed detection of viral antigen and RNA using nanopore sensing and encoded molecular probes.
Ren R, Cai S, Fang X, Wang X, Zhang Z, Damiani M, Hudlerova C, Rosa A, Hope J, Cook NJ, Gorelkin P, Erofeev A, Novak P, Badhan A, Crone M, Freemont P, Taylor GP, Tang L, Edwards C, Shevchuk A, Cherepanov P, Luo Z, Tan W, Korchev Y, Ivanov AP, Edel JB. Ren R, et al. Among authors: badhan a. Nat Commun. 2023 Nov 14;14(1):7362. doi: 10.1038/s41467-023-43004-9. Nat Commun. 2023. PMID: 37963924 Free PMC article.
46 results