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Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans.
Querec TD, Akondy RS, Lee EK, Cao W, Nakaya HI, Teuwen D, Pirani A, Gernert K, Deng J, Marzolf B, Kennedy K, Wu H, Bennouna S, Oluoch H, Miller J, Vencio RZ, Mulligan M, Aderem A, Ahmed R, Pulendran B. Querec TD, et al. Among authors: kennedy k. Nat Immunol. 2009 Jan;10(1):116-125. doi: 10.1038/ni.1688. Epub 2008 Nov 23. Nat Immunol. 2009. PMID: 19029902 Free PMC article.
The Innate Immune Database (IIDB).
Korb M, Rust AG, Thorsson V, Battail C, Li B, Hwang D, Kennedy KA, Roach JC, Rosenberger CM, Gilchrist M, Zak D, Johnson C, Marzolf B, Aderem A, Shmulevich I, Bolouri H. Korb M, et al. BMC Immunol. 2008 Mar 5;9:7. doi: 10.1186/1471-2172-9-7. BMC Immunol. 2008. PMID: 18321385 Free PMC article.
Multiscale representation of genomic signals.
Knijnenburg TA, Ramsey SA, Berman BP, Kennedy KA, Smit AF, Wessels LF, Laird PW, Aderem A, Shmulevich I. Knijnenburg TA, et al. Nat Methods. 2014 Jun;11(6):689-94. doi: 10.1038/nmeth.2924. Epub 2014 Apr 13. Nat Methods. 2014. PMID: 24727652 Free PMC article.
Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses.
Zak DE, Schmitz F, Gold ES, Diercks AH, Peschon JJ, Valvo JS, Niemistö A, Podolsky I, Fallen SG, Suen R, Stolyar T, Johnson CD, Kennedy KA, Hamilton MK, Siggs OM, Beutler B, Aderem A. Zak DE, et al. Proc Natl Acad Sci U S A. 2011 Jul 12;108(28):11536-41. doi: 10.1073/pnas.1107577108. Epub 2011 Jun 27. Proc Natl Acad Sci U S A. 2011. PMID: 21709223 Free PMC article.
Uncovering a macrophage transcriptional program by integrating evidence from motif scanning and expression dynamics.
Ramsey SA, Klemm SL, Zak DE, Kennedy KA, Thorsson V, Li B, Gilchrist M, Gold ES, Johnson CD, Litvak V, Navarro G, Roach JC, Rosenberger CM, Rust AG, Yudkovsky N, Aderem A, Shmulevich I. Ramsey SA, et al. PLoS Comput Biol. 2008 Mar 21;4(3):e1000021. doi: 10.1371/journal.pcbi.1000021. PLoS Comput Biol. 2008. PMID: 18369420 Free PMC article.
2,011 results