Kashemirov BA - Search Results

1

Fluorescently labeled risedronate and related analogues: "magic linker" synthesis.

Kashemirov BA, Bala JL, Chen X, Ebetino FH, Xia Z, Russell RG, Coxon FP, Roelofs AJ, Rogers MJ, McKenna CE. Kashemirov BA, et al. Bioconjug Chem. 2008 Dec;19(12):2308-10. doi: 10.1021/bc800369c. Bioconjug Chem. 2008. PMID: 19032080

2

Carbonylbisphosphonate and (diazomethylene)bisphosphonate analogues of AZT 5(')-diphosphate.

McKenna CE, Kashemirov BA, Rozé CN. McKenna CE, et al. Among authors: kashemirov ba. Bioorg Chem. 2002 Dec;30(6):383-95. doi: 10.1016/s0045-2068(02)00521-7. Bioorg Chem. 2002. PMID: 12642124

3

Synthesis and stability studies of phosphonoformate-amino acid conjugates: a new class of slowly releasing foscarnet prodrugs.

Marma MS, Kashemirov BA, McKenna CE. Marma MS, et al. Among authors: kashemirov ba. Bioorg Med Chem Lett. 2004 Apr 5;14(7):1787-90. doi: 10.1016/j.bmcl.2004.01.016. Bioorg Med Chem Lett. 2004. PMID: 15026072

4

Synthesis and biological activation of an ethylene glycol-linked amino acid conjugate of cyclic cidofovir.

Eriksson U, Hilfinger JM, Kim JS, Mitchell S, Kijek P, Borysko KZ, Breitenbach JM, Drach JC, Kashemirov BA, McKenna CE. Eriksson U, et al. Among authors: kashemirov ba. Bioorg Med Chem Lett. 2007 Feb 1;17(3):583-6. doi: 10.1016/j.bmcl.2006.11.012. Epub 2006 Nov 10. Bioorg Med Chem Lett. 2007. PMID: 17161946 Free PMC article.

5

Modifying the beta,gamma leaving-group bridging oxygen alters nucleotide incorporation efficiency, fidelity, and the catalytic mechanism of DNA polymerase beta.

Sucato CA, Upton TG, Kashemirov BA, Batra VK, Martínek V, Xiang Y, Beard WA, Pedersen LC, Wilson SH, McKenna CE, Florián J, Warshel A, Goodman MF. Sucato CA, et al. Among authors: kashemirov ba. Biochemistry. 2007 Jan 16;46(2):461-71. doi: 10.1021/bi061517b. Biochemistry. 2007. PMID: 17209556

6

Synthesis and biological evaluation of alpha-halogenated bisphosphonate and phosphonocarboxylate analogues of risedronate.

Marma MS, Xia Z, Stewart C, Coxon F, Dunford JE, Baron R, Kashemirov BA, Ebetino FH, Triffitt JT, Russell RG, McKenna CE. Marma MS, et al. Among authors: kashemirov ba. J Med Chem. 2007 Nov 29;50(24):5967-75. doi: 10.1021/jm0702884. Epub 2007 Nov 2. J Med Chem. 2007. PMID: 17975902

7

(R)-beta,gamma-fluoromethylene-dGTP-DNA ternary complex with DNA polymerase beta.

McKenna CE, Kashemirov BA, Upton TG, Batra VK, Goodman MF, Pedersen LC, Beard WA, Wilson SH. McKenna CE, et al. Among authors: kashemirov ba. J Am Chem Soc. 2007 Dec 19;129(50):15412-3. doi: 10.1021/ja072127v. Epub 2007 Nov 22. J Am Chem Soc. 2007. PMID: 18031037 Free PMC article. No abstract available.

8

DNA polymerase beta fidelity: halomethylene-modified leaving groups in pre-steady-state kinetic analysis reveal differences at the chemical transition state.

Sucato CA, Upton TG, Kashemirov BA, Osuna J, Oertell K, Beard WA, Wilson SH, Florián J, Warshel A, McKenna CE, Goodman MF. Sucato CA, et al. Among authors: kashemirov ba. Biochemistry. 2008 Jan 22;47(3):870-9. doi: 10.1021/bi7014162. Epub 2007 Dec 28. Biochemistry. 2008. PMID: 18161950

9

Farnesyl pyrophosphate synthase enantiospecificity with a chiral risedronate analog, [6,7-dihydro-5H-cyclopenta[c]pyridin-7-yl(hydroxy)methylene]bis(phosphonic acid) (NE-10501): Synthetic, structural, and modeling studies.

Deprèle S, Kashemirov BA, Hogan JM, Ebetino FH, Barnett BL, Evdokimov A, McKenna CE. Deprèle S, et al. Among authors: kashemirov ba. Bioorg Med Chem Lett. 2008 May 1;18(9):2878-82. doi: 10.1016/j.bmcl.2008.03.088. Epub 2008 Apr 8. Bioorg Med Chem Lett. 2008. PMID: 18434151

10

Serine peptide phosphoester prodrugs of cyclic cidofovir: synthesis, transport, and antiviral activity.

Eriksson U, Peterson LW, Kashemirov BA, Hilfinger JM, Drach JC, Borysko KZ, Breitenbach JM, Kim JS, Mitchell S, Kijek P, McKenna CE. Eriksson U, et al. Among authors: kashemirov ba. Mol Pharm. 2008 Jul-Aug;5(4):598-609. doi: 10.1021/mp8000099. Epub 2008 May 16. Mol Pharm. 2008. PMID: 18481868 Free PMC article.

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