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The oxidized lipid and lipoxygenase product 12(S)-hydroxyeicosatetraenoic acid induces hypertrophy and fibronectin transcription in vascular smooth muscle cells via p38 MAPK and cAMP response element-binding protein activation. Mediation of angiotensin II effects.
Reddy MA, Thimmalapura PR, Lanting L, Nadler JL, Fatima S, Natarajan R. Reddy MA, et al. Among authors: thimmalapura pr. J Biol Chem. 2002 Mar 22;277(12):9920-8. doi: 10.1074/jbc.M111305200. Epub 2002 Jan 10. J Biol Chem. 2002. PMID: 11786549 Free article.