Freeman GJ - Search Results

1

Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection.

Blackburn SD, Shin H, Haining WN, Zou T, Workman CJ, Polley A, Betts MR, Freeman GJ, Vignali DA, Wherry EJ. Blackburn SD, et al. Among authors: freeman gj. Nat Immunol. 2009 Jan;10(1):29-37. doi: 10.1038/ni.1679. Epub 2008 Nov 30. Nat Immunol. 2009. PMID: 19043418 Free PMC article.

2

The B7-CD28 superfamily.

Sharpe AH, Freeman GJ. Sharpe AH, et al. Among authors: freeman gj. Nat Rev Immunol. 2002 Feb;2(2):116-26. doi: 10.1038/nri727. Nat Rev Immunol. 2002. PMID: 11910893 Review.

3

Differential expression of PD-L1 and PD-L2, ligands for an inhibitory receptor PD-1, in the cells of lymphohematopoietic tissues.

Ishida M, Iwai Y, Tanaka Y, Okazaki T, Freeman GJ, Minato N, Honjo T. Ishida M, et al. Among authors: freeman gj. Immunol Lett. 2002 Oct 21;84(1):57-62. doi: 10.1016/s0165-2478(02)00142-6. Immunol Lett. 2002. PMID: 12161284

4

Endothelial expression of PD-L1 and PD-L2 down-regulates CD8+ T cell activation and cytolysis.

Rodig N, Ryan T, Allen JA, Pang H, Grabie N, Chernova T, Greenfield EA, Liang SC, Sharpe AH, Lichtman AH, Freeman GJ. Rodig N, et al. Among authors: freeman gj. Eur J Immunol. 2003 Nov;33(11):3117-26. doi: 10.1002/eji.200324270. Eur J Immunol. 2003. PMID: 14579280 Free article.

5

Induction of T helper type 1-like regulatory cells that express Foxp3 and protect against airway hyper-reactivity.

Stock P, Akbari O, Berry G, Freeman GJ, Dekruyff RH, Umetsu DT. Stock P, et al. Among authors: freeman gj. Nat Immunol. 2004 Nov;5(11):1149-56. doi: 10.1038/ni1122. Epub 2004 Sep 26. Nat Immunol. 2004. PMID: 15448689

6

Restoring function in exhausted CD8 T cells during chronic viral infection.

Barber DL, Wherry EJ, Masopust D, Zhu B, Allison JP, Sharpe AH, Freeman GJ, Ahmed R. Barber DL, et al. Among authors: freeman gj. Nature. 2006 Feb 9;439(7077):682-7. doi: 10.1038/nature04444. Epub 2005 Dec 28. Nature. 2006. PMID: 16382236

7

PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression.

Day CL, Kaufmann DE, Kiepiela P, Brown JA, Moodley ES, Reddy S, Mackey EW, Miller JD, Leslie AJ, DePierres C, Mncube Z, Duraiswamy J, Zhu B, Eichbaum Q, Altfeld M, Wherry EJ, Coovadia HM, Goulder PJ, Klenerman P, Ahmed R, Freeman GJ, Walker BD. Day CL, et al. Among authors: freeman gj. Nature. 2006 Sep 21;443(7109):350-4. doi: 10.1038/nature05115. Epub 2006 Aug 20. Nature. 2006. PMID: 16921384

8

Reinvigorating exhausted HIV-specific T cells via PD-1-PD-1 ligand blockade.

Freeman GJ, Wherry EJ, Ahmed R, Sharpe AH. Freeman GJ, et al. J Exp Med. 2006 Oct 2;203(10):2223-7. doi: 10.1084/jem.20061800. Epub 2006 Sep 25. J Exp Med. 2006. PMID: 17000870 Free PMC article. Review.

9

Liver-infiltrating lymphocytes in chronic human hepatitis C virus infection display an exhausted phenotype with high levels of PD-1 and low levels of CD127 expression.

Radziewicz H, Ibegbu CC, Fernandez ML, Workowski KA, Obideen K, Wehbi M, Hanson HL, Steinberg JP, Masopust D, Wherry EJ, Altman JD, Rouse BT, Freeman GJ, Ahmed R, Grakoui A. Radziewicz H, et al. Among authors: freeman gj. J Virol. 2007 Mar;81(6):2545-53. doi: 10.1128/JVI.02021-06. Epub 2006 Dec 20. J Virol. 2007. PMID: 17182670 Free PMC article.

10

The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection.

Sharpe AH, Wherry EJ, Ahmed R, Freeman GJ. Sharpe AH, et al. Among authors: freeman gj. Nat Immunol. 2007 Mar;8(3):239-45. doi: 10.1038/ni1443. Nat Immunol. 2007. PMID: 17304234 Review.

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