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Cytochrome P450 6M2 from the malaria vector Anopheles gambiae metabolizes pyrethroids: Sequential metabolism of deltamethrin revealed.
Stevenson BJ, Bibby J, Pignatelli P, Muangnoicharoen S, O'Neill PM, Lian LY, Müller P, Nikou D, Steven A, Hemingway J, Sutcliffe MJ, Paine MJ. Stevenson BJ, et al. Among authors: steven a. Insect Biochem Mol Biol. 2011 Jul;41(7):492-502. doi: 10.1016/j.ibmb.2011.02.003. Epub 2011 Feb 13. Insect Biochem Mol Biol. 2011. PMID: 21324359
Albendazole and antibiotics synergize to deliver short-course anti-Wolbachia curative treatments in preclinical models of filariasis.
Turner JD, Sharma R, Al Jayoussi G, Tyrer HE, Gamble J, Hayward L, Priestley RS, Murphy EA, Davies J, Waterhouse D, Cook DAN, Clare RH, Cassidy A, Steven A, Johnston KL, McCall J, Ford L, Hemingway J, Ward SA, Taylor MJ. Turner JD, et al. Among authors: steven a. Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):E9712-E9721. doi: 10.1073/pnas.1710845114. Epub 2017 Oct 23. Proc Natl Acad Sci U S A. 2017. PMID: 29078351 Free PMC article.
Wolbachia depletion blocks transmission of lymphatic filariasis by preventing chitinase-dependent parasite exsheathment.
Quek S, Cook DAN, Wu Y, Marriott AE, Steven A, Johnston KL, Ford L, Archer J, Hemingway J, Ward SA, Wagstaff SC, Turner JD, Taylor MJ. Quek S, et al. Among authors: steven a. Proc Natl Acad Sci U S A. 2022 Apr 12;119(15):e2120003119. doi: 10.1073/pnas.2120003119. Epub 2022 Apr 4. Proc Natl Acad Sci U S A. 2022. PMID: 35377795 Free PMC article.
AWZ1066S, a highly specific anti-Wolbachia drug candidate for a short-course treatment of filariasis.
Hong WD, Benayoud F, Nixon GL, Ford L, Johnston KL, Clare RH, Cassidy A, Cook DAN, Siu A, Shiotani M, Webborn PJH, Kavanagh S, Aljayyoussi G, Murphy E, Steven A, Archer J, Struever D, Frohberger SJ, Ehrens A, Hübner MP, Hoerauf A, Roberts AP, Hubbard ATM, Tate EW, Serwa RA, Leung SC, Qie L, Berry NG, Gusovsky F, Hemingway J, Turner JD, Taylor MJ, Ward SA, O'Neill PM. Hong WD, et al. Among authors: steven a. Proc Natl Acad Sci U S A. 2019 Jan 22;116(4):1414-1419. doi: 10.1073/pnas.1816585116. Epub 2019 Jan 7. Proc Natl Acad Sci U S A. 2019. PMID: 30617067 Free PMC article.
492 results