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Page 1
Increase in insulin sensitivity by the association of chicoric acid and chlorogenic acid contained in a natural chicoric acid extract (NCRAE) of chicory (Cichorium intybus L.) for an antidiabetic effect.
Ferrare K, Bidel LPR, Awwad A, Poucheret P, Cazals G, Lazennec F, Azay-Milhau J, Tournier M, Lajoix AD, Tousch D. Ferrare K, et al. Among authors: azay milhau j. J Ethnopharmacol. 2018 Apr 6;215:241-248. doi: 10.1016/j.jep.2017.12.035. Epub 2018 Jan 9. J Ethnopharmacol. 2018. PMID: 29325917
Glucose-derived spiro-isoxazolines are anti-hyperglycemic agents against type 2 diabetes through glycogen phosphorylase inhibition.
Goyard D, Kónya B, Chajistamatiou AS, Chrysina ED, Leroy J, Balzarin S, Tournier M, Tousch D, Petit P, Duret C, Maurel P, Somsák L, Docsa T, Gergely P, Praly JP, Azay-Milhau J, Vidal S. Goyard D, et al. Among authors: azay milhau j. Eur J Med Chem. 2016 Jan 27;108:444-454. doi: 10.1016/j.ejmech.2015.12.004. Epub 2015 Dec 10. Eur J Med Chem. 2016. PMID: 26708111
Adipose tissue derived-factors impaired pancreatic β-cell function in diabetes.
Rebuffat SA, Sidot E, Guzman C, Azay-Milhau J, Jover B, Lajoix AD, Peraldi-Roux S. Rebuffat SA, et al. Among authors: azay milhau j. Biochim Biophys Acta Mol Basis Dis. 2018 Oct;1864(10):3378-3387. doi: 10.1016/j.bbadis.2018.07.024. Epub 2018 Jul 23. Biochim Biophys Acta Mol Basis Dis. 2018. PMID: 30048752 Free article.
Glucose-based spiro-oxathiazoles as in vivo anti-hyperglycemic agents through glycogen phosphorylase inhibition.
Goyard D, Kónya B, Czifrák K, Larini P, Demontrond F, Leroy J, Balzarin S, Tournier M, Tousch D, Petit P, Duret C, Maurel P, Docsa T, Gergely P, Somsák L, Praly JP, Azay-Milhau J, Vidal S. Goyard D, et al. Among authors: azay milhau j. Org Biomol Chem. 2020 Feb 7;18(5):931-940. doi: 10.1039/c9ob01190k. Epub 2020 Jan 10. Org Biomol Chem. 2020. PMID: 31922157
Reduced production of isoprostanes by peri-pancreatic adipose tissue from Zucker fa/fa rats as a new mechanism for β-cell compensation in insulin resistance and obesity.
Laget J, Vigor C, Nouvel A, Rocher A, Leroy J, Jeanson L, Reversat G, Oger C, Galano JM, Durand T, Péraldi-Roux S, Azay-Milhau J, Lajoix AD. Laget J, et al. Among authors: azay milhau j. Free Radic Biol Med. 2022 Mar;182:160-170. doi: 10.1016/j.freeradbiomed.2022.02.013. Epub 2022 Feb 25. Free Radic Biol Med. 2022. PMID: 35227851