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The design, synthesis, and antiviral activity of 4'-azidocytidine analogues against hepatitis C virus replication: the discovery of 4'-azidoarabinocytidine.
Smith DB, Kalayanov G, Sund C, Winqvist A, Pinho P, Maltseva T, Morisson V, Leveque V, Rajyaguru S, Le Pogam S, Najera I, Benkestock K, Zhou XX, Maag H, Cammack N, Martin JA, Swallow S, Johansson NG, Klumpp K, Smith M. Smith DB, et al. Among authors: maltseva t. J Med Chem. 2009 Jan 8;52(1):219-23. doi: 10.1021/jm800981y. J Med Chem. 2009. PMID: 19055482
2'-deoxy-4'-azido nucleoside analogs are highly potent inhibitors of hepatitis C virus replication despite the lack of 2'-alpha-hydroxyl groups.
Klumpp K, Kalayanov G, Ma H, Le Pogam S, Leveque V, Jiang WR, Inocencio N, De Witte A, Rajyaguru S, Tai E, Chanda S, Irwin MR, Sund C, Winqist A, Maltseva T, Eriksson S, Usova E, Smith M, Alker A, Najera I, Cammack N, Martin JA, Johansson NG, Smith DB. Klumpp K, et al. Among authors: maltseva t. J Biol Chem. 2008 Jan 25;283(4):2167-75. doi: 10.1074/jbc.M708929200. Epub 2007 Nov 14. J Biol Chem. 2008. PMID: 18003608 Free article.
The design, synthesis, and antiviral activity of monofluoro and difluoro analogues of 4'-azidocytidine against hepatitis C virus replication: the discovery of 4'-azido-2'-deoxy-2'-fluorocytidine and 4'-azido-2'-dideoxy-2',2'-difluorocytidine.
Smith DB, Kalayanov G, Sund C, Winqvist A, Maltseva T, Leveque VJ, Rajyaguru S, Le Pogam S, Najera I, Benkestock K, Zhou XX, Kaiser AC, Maag H, Cammack N, Martin JA, Swallow S, Johansson NG, Klumpp K, Smith M. Smith DB, et al. Among authors: maltseva t. J Med Chem. 2009 May 14;52(9):2971-8. doi: 10.1021/jm801595c. J Med Chem. 2009. PMID: 19341305
Do the 16 mer, 5'-GUGGUCUGAUGAGGCC-3' and the 25 mer, 5'-GGCCGAAACUCGUAAGAGUCACCAC-3', form a hammerhead ribozyme structure in physiological conditions? An NMR and UV thermodynamic study.
Zamaratski E, Trifonova A, Acharya P, Isaksson J, Maltseva T, Chattopadhayaya J. Zamaratski E, et al. Among authors: maltseva t. Nucleosides Nucleotides Nucleic Acids. 2001 Apr-Jul;20(4-7):1219-23. doi: 10.1081/NCN-100002522. Nucleosides Nucleotides Nucleic Acids. 2001. PMID: 11562989
53 results