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A mutant-cell library for systematic analysis of heparan sulfate structure-function relationships.
Qiu H, Shi S, Yue J, Xin M, Nairn AV, Lin L, Liu X, Li G, Archer-Hartmann SA, Dela Rosa M, Galizzi M, Wang S, Zhang F, Azadi P, van Kuppevelt TH, Cardoso WV, Kimata K, Ai X, Moremen KW, Esko JD, Linhardt RJ, Wang L. Qiu H, et al. Among authors: van kuppevelt th. Nat Methods. 2018 Nov;15(11):889-899. doi: 10.1038/s41592-018-0189-6. Epub 2018 Oct 30. Nat Methods. 2018. PMID: 30377379 Free PMC article.
Changes in heparan sulfate are associated with delayed wound repair, altered cell migration, adhesion and contractility in the galactosyltransferase I (beta4GalT-7) deficient form of Ehlers-Danlos syndrome.
Götte M, Spillmann D, Yip GW, Versteeg E, Echtermeyer FG, van Kuppevelt TH, Kiesel L. Götte M, et al. Among authors: van kuppevelt th. Hum Mol Genet. 2008 Apr 1;17(7):996-1009. doi: 10.1093/hmg/ddm372. Epub 2007 Dec 24. Hum Mol Genet. 2008. PMID: 18158310
Modulation of heparan sulfate in the glomerular endothelial glycocalyx decreases leukocyte influx during experimental glomerulonephritis.
Rops AL, Loeven MA, van Gemst JJ, Eversen I, Van Wijk XM, Dijkman HB, van Kuppevelt TH, Berden JH, Rabelink TJ, Esko JD, van der Vlag J. Rops AL, et al. Among authors: van wijk xm, van gemst jj, van kuppevelt th, van der vlag j. Kidney Int. 2014 Nov;86(5):932-42. doi: 10.1038/ki.2014.115. Epub 2014 Apr 23. Kidney Int. 2014. PMID: 24759151 Free article.
Loss of Hs3st3a1 or Hs3st3b1 enzymes alters heparan sulfate to reduce epithelial morphogenesis and adult salivary gland function.
Patel VN, Pineda DL, Berenstein E, Hauser BR, Choi S, Prochazkova M, Zheng C, Goldsmith CM, van Kuppevelt TH, Kulkarni A, Song Y, Linhardt RJ, Chibly AM, Hoffman MP. Patel VN, et al. Among authors: van kuppevelt th. Matrix Biol. 2021 Sep;103-104:37-57. doi: 10.1016/j.matbio.2021.10.002. Epub 2021 Oct 12. Matrix Biol. 2021. PMID: 34653670 Free PMC article.
362 results