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The fatty acid biosynthesis enzyme FabI plays a key role in the development of liver-stage malarial parasites.
Yu M, Kumar TR, Nkrumah LJ, Coppi A, Retzlaff S, Li CD, Kelly BJ, Moura PA, Lakshmanan V, Freundlich JS, Valderramos JC, Vilcheze C, Siedner M, Tsai JH, Falkard B, Sidhu AB, Purcell LA, Gratraud P, Kremer L, Waters AP, Schiehser G, Jacobus DP, Janse CJ, Ager A, Jacobs WR Jr, Sacchettini JC, Heussler V, Sinnis P, Fidock DA. Yu M, et al. Among authors: waters ap. Cell Host Microbe. 2008 Dec 11;4(6):567-78. doi: 10.1016/j.chom.2008.11.001. Cell Host Microbe. 2008. PMID: 19064257 Free PMC article.
Gene disruption of Plasmodium falciparum p52 results in attenuation of malaria liver stage development in cultured primary human hepatocytes.
van Schaijk BC, Janse CJ, van Gemert GJ, van Dijk MR, Gego A, Franetich JF, van de Vegte-Bolmer M, Yalaoui S, Silvie O, Hoffman SL, Waters AP, Mazier D, Sauerwein RW, Khan SM. van Schaijk BC, et al. Among authors: waters ap. PLoS One. 2008;3(10):e3549. doi: 10.1371/journal.pone.0003549. Epub 2008 Oct 28. PLoS One. 2008. PMID: 18958160 Free PMC article.
207 results