Enge M - Search Results

1

Tumor-specific induction of apoptosis by a p53-reactivating compound.

Hedström E, Issaeva N, Enge M, Selivanova G. Hedström E, et al. Among authors: enge m. Exp Cell Res. 2009 Feb 1;315(3):451-61. doi: 10.1016/j.yexcr.2008.11.009. Epub 2008 Dec 3. Exp Cell Res. 2009. PMID: 19071110

2

Small molecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors.

Issaeva N, Bozko P, Enge M, Protopopova M, Verhoef LG, Masucci M, Pramanik A, Selivanova G. Issaeva N, et al. Among authors: enge m. Nat Med. 2004 Dec;10(12):1321-8. doi: 10.1038/nm1146. Epub 2004 Nov 21. Nat Med. 2004. PMID: 15558054

3

MDM2-dependent downregulation of p21 and hnRNP K provides a switch between apoptosis and growth arrest induced by pharmacologically activated p53.

Enge M, Bao W, Hedström E, Jackson SP, Moumen A, Selivanova G. Enge M, et al. Cancer Cell. 2009 Mar 3;15(3):171-83. doi: 10.1016/j.ccr.2009.01.019. Cancer Cell. 2009. PMID: 19249676 Free article.

4

Ablation of key oncogenic pathways by RITA-reactivated p53 is required for efficient apoptosis.

Grinkevich VV, Nikulenkov F, Shi Y, Enge M, Bao W, Maljukova A, Gluch A, Kel A, Sangfelt O, Selivanova G. Grinkevich VV, et al. Among authors: enge m. Cancer Cell. 2009 May 5;15(5):441-53. doi: 10.1016/j.ccr.2009.03.021. Cancer Cell. 2009. PMID: 19411072 Free article.

5

Inhibition of glycolytic enzymes mediated by pharmacologically activated p53: targeting Warburg effect to fight cancer.

Zawacka-Pankau J, Grinkevich VV, Hünten S, Nikulenkov F, Gluch A, Li H, Enge M, Kel A, Selivanova G. Zawacka-Pankau J, et al. Among authors: enge m. J Biol Chem. 2011 Dec 2;286(48):41600-41615. doi: 10.1074/jbc.M111.240812. Epub 2011 Aug 23. J Biol Chem. 2011. PMID: 21862591 Free PMC article.

6

Pharmacological activation of p53 triggers anticancer innate immune response through induction of ULBP2.

Li H, Lakshmikanth T, Garofalo C, Enge M, Spinnler C, Anichini A, Szekely L, Kärre K, Carbone E, Selivanova G. Li H, et al. Among authors: enge m. Cell Cycle. 2011 Oct 1;10(19):3346-58. doi: 10.4161/cc.10.19.17630. Epub 2011 Oct 1. Cell Cycle. 2011. PMID: 21941086

7

Protein kinase Cα (PKCα) regulates p53 localization and melanoma cell survival downstream of integrin αv in three-dimensional collagen and in vivo.

Smith SD, Enge M, Bao W, Thullberg M, Costa TD, Olofsson H, Gashi B, Selivanova G, Strömblad S. Smith SD, et al. Among authors: enge m. J Biol Chem. 2012 Aug 24;287(35):29336-47. doi: 10.1074/jbc.M112.341917. Epub 2012 Jul 6. J Biol Chem. 2012. PMID: 22773839 Free PMC article.

8

Ablation of Key Oncogenic Pathways by RITA-Reactivated p53 Is Required for Efficient Apoptosis.

Grinkevich VV, Nikulenkov F, Shi Y, Enge M, Bao W, Maljukova A, Gluch A, Kel A, Sangfelt O, Selivanova G. Grinkevich VV, et al. Among authors: enge m. Cancer Cell. 2017 May 8;31(5):724-726. doi: 10.1016/j.ccell.2017.04.014. Cancer Cell. 2017. PMID: 28486110 Free article. No abstract available.

9

DNA-binding specificities of human transcription factors.

Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. Jolma A, et al. Among authors: enge m. Cell. 2013 Jan 17;152(1-2):327-39. doi: 10.1016/j.cell.2012.12.009. Cell. 2013. PMID: 23332764 Free article.

10

Transcription factor binding in human cells occurs in dense clusters formed around cohesin anchor sites.

Yan J, Enge M, Whitington T, Dave K, Liu J, Sur I, Schmierer B, Jolma A, Kivioja T, Taipale M, Taipale J. Yan J, et al. Among authors: enge m. Cell. 2013 Aug 15;154(4):801-13. doi: 10.1016/j.cell.2013.07.034. Cell. 2013. PMID: 23953112 Free article.

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