Baron RA - Search Results

1

Phosphonocarboxylates inhibit the second geranylgeranyl addition by Rab geranylgeranyl transferase.

Baron RA, Tavaré R, Figueiredo AC, Błazewska KM, Kashemirov BA, McKenna CE, Ebetino FH, Taylor A, Rogers MJ, Coxon FP, Seabra MC. Baron RA, et al. J Biol Chem. 2009 Mar 13;284(11):6861-8. doi: 10.1074/jbc.M806952200. Epub 2008 Dec 11. J Biol Chem. 2009. PMID: 19074143 Free PMC article.

2

Rab geranylgeranylation occurs preferentially via the pre-formed REP-RGGT complex and is regulated by geranylgeranyl pyrophosphate.

Baron RA, Seabra MC. Baron RA, et al. Biochem J. 2008 Oct 1;415(1):67-75. doi: 10.1042/BJ20080662. Biochem J. 2008. PMID: 18532927

3

Rab3GEP is the non-redundant guanine nucleotide exchange factor for Rab27a in melanocytes.

Figueiredo AC, Wasmeier C, Tarafder AK, Ramalho JS, Baron RA, Seabra MC. Figueiredo AC, et al. Among authors: baron ra. J Biol Chem. 2008 Aug 22;283(34):23209-16. doi: 10.1074/jbc.M804134200. Epub 2008 Jun 17. J Biol Chem. 2008. PMID: 18559336 Free PMC article.

4

Synthesis, chiral high performance liquid chromatographic resolution and enantiospecific activity of a potent new geranylgeranyl transferase inhibitor, 2-hydroxy-3-imidazo[1,2-a]pyridin-3-yl-2-phosphonopropionic acid.

McKenna CE, Kashemirov BA, Błazewska KM, Mallard-Favier I, Stewart CA, Rojas J, Lundy MW, Ebetino FH, Baron RA, Dunford JE, Kirsten ML, Seabra MC, Bala JL, Marma MS, Rogers MJ, Coxon FP. McKenna CE, et al. Among authors: baron ra. J Med Chem. 2010 May 13;53(9):3454-64. doi: 10.1021/jm900232u. J Med Chem. 2010. PMID: 20394422

5

Thematic review series: lipid posttranslational modifications. geranylgeranylation of Rab GTPases.

Leung KF, Baron R, Seabra MC. Leung KF, et al. J Lipid Res. 2006 Mar;47(3):467-75. doi: 10.1194/jlr.R500017-JLR200. Epub 2006 Jan 9. J Lipid Res. 2006. PMID: 16401880 Free article. Review.

6

Rab GTPases containing a CAAX motif are processed post-geranylgeranylation by proteolysis and methylation.

Leung KF, Baron R, Ali BR, Magee AI, Seabra MC. Leung KF, et al. J Biol Chem. 2007 Jan 12;282(2):1487-97. doi: 10.1074/jbc.M605557200. Epub 2006 Nov 18. J Biol Chem. 2007. PMID: 17114793 Free article.

7

The gunmetal mouse reveals Rab geranylgeranyl transferase to be the major molecular target of phosphonocarboxylate analogues of bisphosphonates.

Coxon FP, Taylor A, Stewart CA, Baron R, Seabra MC, Ebetino FH, Rogers MJ. Coxon FP, et al. Bone. 2011 Jul;49(1):111-21. doi: 10.1016/j.bone.2011.03.686. Epub 2011 Mar 21. Bone. 2011. PMID: 21419243

8

Synthesis, stereochemistry and SAR of a series of minodronate analogues as RGGT inhibitors.

Błażewska KM, Ni F, Haiges R, Kashemirov BA, Coxon FP, Stewart CA, Baron R, Rogers MJ, Seabra MC, Ebetino FH, McKenna CE. Błażewska KM, et al. Eur J Med Chem. 2011 Oct;46(10):4820-6. doi: 10.1016/j.ejmech.2011.04.063. Epub 2011 May 7. Eur J Med Chem. 2011. PMID: 21889236

9

Synthesis and biological evaluation of alpha-halogenated bisphosphonate and phosphonocarboxylate analogues of risedronate.

Marma MS, Xia Z, Stewart C, Coxon F, Dunford JE, Baron R, Kashemirov BA, Ebetino FH, Triffitt JT, Russell RG, McKenna CE. Marma MS, et al. J Med Chem. 2007 Nov 29;50(24):5967-75. doi: 10.1021/jm0702884. Epub 2007 Nov 2. J Med Chem. 2007. PMID: 17975902

10

Rab1a and Rab5a preferentially bind to binary lipid compositions with higher stored curvature elastic energy.

Kirsten ML, Baron RA, Seabra MC, Ces O. Kirsten ML, et al. Among authors: baron ra. Mol Membr Biol. 2013 Jul;30(4):303-14. doi: 10.3109/09687688.2013.818725. Mol Membr Biol. 2013. PMID: 23815289 Free article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

44 results

Search Page

Filters