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In vivo dynamics of stable chronic lymphocytic leukemia inversely correlate with somatic hypermutation levels and suggest no major leukemic turnover in bone marrow.
van Gent R, Kater AP, Otto SA, Jaspers A, Borghans JA, Vrisekoop N, Ackermans MA, Ruiter AF, Wittebol S, Eldering E, van Oers MH, Tesselaar K, Kersten MJ, Miedema F. van Gent R, et al. Among authors: otto sa. Cancer Res. 2008 Dec 15;68(24):10137-44. doi: 10.1158/0008-5472.CAN-08-2325. Cancer Res. 2008. PMID: 19074880
Quantification of naive and memory T-cell turnover during HIV-1 infection.
Vrisekoop N, Drylewicz J, Van Gent R, Mugwagwa T, Van Lelyveld SF, Veel E, Otto SA, Ackermans MT, Vermeulen JN, Huidekoper HH, Prins JM, Miedema F, de Boer RJ, Tesselaar K, Borghans JA. Vrisekoop N, et al. Among authors: otto sa. AIDS. 2015 Oct 23;29(16):2071-80. doi: 10.1097/QAD.0000000000000822. AIDS. 2015. PMID: 26213901
Restoration of the CD4 T cell compartment after long-term highly active antiretroviral therapy without phenotypical signs of accelerated immunological aging.
Vrisekoop N, van Gent R, de Boer AB, Otto SA, Borleffs JC, Steingrover R, Prins JM, Kuijpers TW, Wolfs TF, Geelen SP, Vulto I, Lansdorp P, Tesselaar K, Borghans JA, Miedema F. Vrisekoop N, et al. Among authors: otto sa. J Immunol. 2008 Jul 15;181(2):1573-81. doi: 10.4049/jimmunol.181.2.1573. J Immunol. 2008. PMID: 18606713
Maintenance of peripheral naive T cells is sustained by thymus output in mice but not humans.
den Braber I, Mugwagwa T, Vrisekoop N, Westera L, Mögling R, de Boer AB, Willems N, Schrijver EH, Spierenburg G, Gaiser K, Mul E, Otto SA, Ruiter AF, Ackermans MT, Miedema F, Borghans JA, de Boer RJ, Tesselaar K. den Braber I, et al. Among authors: otto sa. Immunity. 2012 Feb 24;36(2):288-97. doi: 10.1016/j.immuni.2012.02.006. Immunity. 2012. PMID: 22365666 Free article.
Reconciling Longitudinal Naive T-Cell and TREC Dynamics during HIV-1 Infection.
Drylewicz J, Vrisekoop N, Mugwagwa T, de Boer AB, Otto SA, Hazenberg MD, Tesselaar K, de Boer RJ, Borghans JA. Drylewicz J, et al. Among authors: otto sa. PLoS One. 2016 Mar 24;11(3):e0152513. doi: 10.1371/journal.pone.0152513. eCollection 2016. PLoS One. 2016. PMID: 27010200 Free PMC article.
75 results