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Aurora-A kinase is essential for bipolar spindle formation and early development.
Cowley DO, Rivera-Pérez JA, Schliekelman M, He YJ, Oliver TG, Lu L, O'Quinn R, Salmon ED, Magnuson T, Van Dyke T. Cowley DO, et al. Among authors: lu l. Mol Cell Biol. 2009 Feb;29(4):1059-71. doi: 10.1128/MCB.01062-08. Epub 2008 Dec 15. Mol Cell Biol. 2009. PMID: 19075002 Free PMC article.
Loss of Brca1 and Trp53 in adult mouse mammary ductal epithelium results in development of hormone receptor-positive or hormone receptor-negative tumors, depending on inactivation of Rb family proteins.
Szabova L, Gordon MB, Lu L, Pate N, Bassel L, Iacovelli AJ, Karim B, Homan PJ, Householder DB, Guerin TM, Burkett S, Day AM, Custer W, Weaver Ohler Z. Szabova L, et al. Among authors: lu l. Breast Cancer Res. 2022 Nov 4;24(1):75. doi: 10.1186/s13058-022-01566-4. Breast Cancer Res. 2022. PMID: 36333737 Free PMC article.
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