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Anthranilimide-based glycogen phosphorylase inhibitors for the treatment of type 2 diabetes: 1. Identification of 1-amino-1-cycloalkyl carboxylic acid headgroups.
Sparks SM, Banker P, Bickett DM, Carter HL, Clancy DC, Dickerson SH, Dwornik KA, Garrido DM, Golden PL, Nolte RT, Peat AJ, Sheckler LR, Tavares FX, Thomson SA, Wang L, Weiel JE. Sparks SM, et al. Among authors: golden pl. Bioorg Med Chem Lett. 2009 Feb 1;19(3):976-80. doi: 10.1016/j.bmcl.2008.11.085. Epub 2008 Nov 27. Bioorg Med Chem Lett. 2009. PMID: 19095442
Amino acid anthranilamide derivatives as a new class of glycogen phosphorylase inhibitors.
Evans KA, Li YH, Coppo FT, Graybill TL, Cichy-Knight M, Patel M, Gale J, Li H, Thrall SH, Tew D, Tavares F, Thomson SA, Weiel JE, Boucheron JA, Clancy DC, Epperly AH, Golden PL. Evans KA, et al. Among authors: golden pl. Bioorg Med Chem Lett. 2008 Jul 15;18(14):4068-71. doi: 10.1016/j.bmcl.2008.05.102. Epub 2008 Jun 12. Bioorg Med Chem Lett. 2008. PMID: 18554908
Anthranilimide-based glycogen phosphorylase inhibitors for the treatment of Type 2 diabetes: 2. Optimization of serine and threonine ether amino acid residues.
Sparks SM, Banker P, Bickett DM, Clancy DC, Dickerson SH, Garrido DM, Golden PL, Peat AJ, Sheckler LR, Tavares FX, Thomson SA, Weiel JE. Sparks SM, et al. Among authors: golden pl. Bioorg Med Chem Lett. 2009 Feb 1;19(3):981-5. doi: 10.1016/j.bmcl.2008.11.084. Epub 2008 Nov 27. Bioorg Med Chem Lett. 2009. PMID: 19095443
Tetrahydrocarbazole amides with potent activity against human papillomaviruses.
Gudmundsson KS, Boggs SD, Sebahar PR, Richardson LD, Spaltenstein A, Golden P, Sethna PB, Brown KW, Moniri K, Harvey R, Romines KR. Gudmundsson KS, et al. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4110-4. doi: 10.1016/j.bmcl.2009.06.001. Epub 2009 Jun 6. Bioorg Med Chem Lett. 2009. PMID: 19556128
Synthesis and antiviral activity of 7-benzyl-4-hydroxy-1,5-naphthyridin-2(1H)-one HIV integrase inhibitors.
Boros EE, Edwards CE, Foster SA, Fuji M, Fujiwara T, Garvey EP, Golden PL, Hazen RJ, Jeffrey JL, Johns BA, Kawasuji T, Kiyama R, Koble CS, Kurose N, Miller WH, Mote AL, Murai H, Sato A, Thompson JB, Woodward MC, Yoshinaga T. Boros EE, et al. Among authors: golden pl. J Med Chem. 2009 May 14;52(9):2754-61. doi: 10.1021/jm801404b. J Med Chem. 2009. PMID: 19374386
25 results