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Lentiviral vectors encoding human immunodeficiency virus type 1 (HIV-1)-specific T-cell receptor genes efficiently convert peripheral blood CD8 T lymphocytes into cytotoxic T lymphocytes with potent in vitro and in vivo HIV-1-specific inhibitory activity.
Joseph A, Zheng JH, Follenzi A, Dilorenzo T, Sango K, Hyman J, Chen K, Piechocka-Trocha A, Brander C, Hooijberg E, Vignali DA, Walker BD, Goldstein H. Joseph A, et al. Among authors: zheng jh. J Virol. 2008 Mar;82(6):3078-89. doi: 10.1128/JVI.01812-07. Epub 2008 Jan 9. J Virol. 2008. PMID: 18184707 Free PMC article.
Increased in vivo activation of microglia and astrocytes in the brains of mice transgenic for an infectious R5 human immunodeficiency virus type 1 provirus and for CD4-specific expression of human cyclin T1 in response to stimulation by lipopolysaccharides.
Sun J, Zheng JH, Zhao M, Lee S, Goldstein H. Sun J, et al. Among authors: zheng jh. J Virol. 2008 Jun;82(11):5562-72. doi: 10.1128/JVI.02618-07. Epub 2008 Mar 19. J Virol. 2008. PMID: 18353948 Free PMC article.
Identification of granulocyte-macrophage colony-stimulating factor and lipopolysaccharide-induced signal transduction pathways that synergize to stimulate HIV type 1 production by monocytes from HIV type 1 transgenic mice.
Osiecki K, Xie L, Zheng JH, Squires R, Pettoello-Mantovani M, Goldstein H. Osiecki K, et al. Among authors: zheng jh. AIDS Res Hum Retroviruses. 2005 Feb;21(2):125-39. doi: 10.1089/aid.2005.21.125. AIDS Res Hum Retroviruses. 2005. PMID: 15725751
CD4-specific transgenic expression of human cyclin T1 markedly increases human immunodeficiency virus type 1 (HIV-1) production by CD4+ T lymphocytes and myeloid cells in mice transgenic for a provirus encoding a monocyte-tropic HIV-1 isolate.
Sun J, Soos T, Kewalramani VN, Osiecki K, Zheng JH, Falkin L, Santambrogio L, Littman DR, Goldstein H. Sun J, et al. Among authors: zheng jh. J Virol. 2006 Feb;80(4):1850-62. doi: 10.1128/JVI.80.4.1850-1862.2006. J Virol. 2006. PMID: 16439541 Free PMC article.
485 results