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Phase I pharmacokinetic and pharmacodynamic study of the oral protein kinase C beta-inhibitor enzastaurin in combination with gemcitabine and cisplatin in patients with advanced cancer.
Rademaker-Lakhai JM, Beerepoot LV, Mehra N, Radema SA, van Maanen R, Vermaat JS, Witteveen EO, Visseren-Grul CM, Musib L, Enas N, van Hal G, Beijnen JH, Schellens JH, Voest EE. Rademaker-Lakhai JM, et al. Clin Cancer Res. 2007 Aug 1;13(15 Pt 1):4474-81. doi: 10.1158/1078-0432.CCR-06-2912. Clin Cancer Res. 2007. PMID: 17671132 Clinical Trial.
A phase II multicenter study of two different dosages of pemetrexed given in combination with cyclophosphamide as first-line treatment in patients with locally advanced or metastatic breast cancer.
Dittrich C, Solska E, Manikhas A, Eniu A, Tjulandin S, Anghel R, Musib L, Frimodt-Moller B, Liu Y, Krejcy K, Láng I. Dittrich C, et al. Cancer Invest. 2012 May;30(4):309-16. doi: 10.3109/07357907.2012.658938. Epub 2012 Apr 2. Cancer Invest. 2012. PMID: 22468806 Clinical Trial.
A phase I trial of enzastaurin in patients with recurrent gliomas.
Kreisl TN, Kim L, Moore K, Duic P, Kotliarova S, Walling J, Musib L, Thornton D, Albert PS, Fine HA. Kreisl TN, et al. Clin Cancer Res. 2009 May 15;15(10):3617-23. doi: 10.1158/1078-0432.CCR-08-3071. Epub 2009 May 5. Clin Cancer Res. 2009. PMID: 19417015 Free PMC article. Clinical Trial.
Development and validation of a drug activity biomarker that shows target inhibition in cancer patients receiving enzastaurin, a novel protein kinase C-beta inhibitor.
Green LJ, Marder P, Ray C, Cook CA, Jaken S, Musib LC, Herbst RS, Carducci M, Britten CD, Basche M, Eckhardt SG, Thornton D. Green LJ, et al. Among authors: musib lc. Clin Cancer Res. 2006 Jun 1;12(11 Pt 1):3408-15. doi: 10.1158/1078-0432.CCR-05-2231. Clin Cancer Res. 2006. PMID: 16740765
49 results