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YS 51, 1-(beta-naphtylmethyl)-6,7-dihydroxy-1,2,3,4,-tetrahydroisoquinoline, protects endothelial cells against hydrogen peroxide-induced injury via carbon monoxide derived from heme oxygenase-1.
Heo JM, Kim HJ, Ha YM, Park MK, Kang YJ, Lee YS, Seo HG, Lee JH, Yun-Choi HS, Chang KC. Heo JM, et al. Among authors: park mk. Biochem Pharmacol. 2007 Nov 1;74(9):1361-70. doi: 10.1016/j.bcp.2007.07.023. Epub 2007 Jul 21. Biochem Pharmacol. 2007. PMID: 17719563
β₁-adrenergic receptor-mediated HO-1 induction, via PI3K and p38 MAPK, by isoproterenol in RAW 264.7 cells leads to inhibition of HMGB1 release in LPS-activated RAW 264.7 cells and increases in survival rate of CLP-induced septic mice.
Ha YM, Ham SA, Kim YM, Lee YS, Kim HJ, Seo HG, Lee JH, Park MK, Chang KC. Ha YM, et al. Among authors: park mk. Biochem Pharmacol. 2011 Oct 1;82(7):769-77. doi: 10.1016/j.bcp.2011.06.041. Epub 2011 Jul 5. Biochem Pharmacol. 2011. PMID: 21763292
1,105 results