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Ventricular phosphodiesterase-5 expression is increased in patients with advanced heart failure and contributes to adverse ventricular remodeling after myocardial infarction in mice.
Pokreisz P, Vandenwijngaert S, Bito V, Van den Bergh A, Lenaerts I, Busch C, Marsboom G, Gheysens O, Vermeersch P, Biesmans L, Liu X, Gillijns H, Pellens M, Van Lommel A, Buys E, Schoonjans L, Vanhaecke J, Verbeken E, Sipido K, Herijgers P, Bloch KD, Janssens SP. Pokreisz P, et al. Circulation. 2009 Jan 27;119(3):408-16. doi: 10.1161/CIRCULATIONAHA.108.822072. Epub 2009 Jan 12. Circulation. 2009. PMID: 19139381 Free PMC article.
Cardiomyocyte-specific overexpression of nitric oxide synthase 3 improves left ventricular performance and reduces compensatory hypertrophy after myocardial infarction.
Janssens S, Pokreisz P, Schoonjans L, Pellens M, Vermeersch P, Tjwa M, Jans P, Scherrer-Crosbie M, Picard MH, Szelid Z, Gillijns H, Van de Werf F, Collen D, Bloch KD. Janssens S, et al. Among authors: pokreisz p. Circ Res. 2004 May 14;94(9):1256-62. doi: 10.1161/01.RES.0000126497.38281.23. Epub 2004 Mar 25. Circ Res. 2004. PMID: 15044322 Free article.
[Possibilities for cardiovascular gene therapy].
Szelid ZL, Pokreisz P, Janssens S, Polák G. Szelid ZL, et al. Among authors: pokreisz p. Orv Hetil. 2005 May 29;146(22):1189-96. Orv Hetil. 2005. PMID: 15997664 Review. Hungarian.
Cytochrome P450 epoxygenase gene function in hypoxic pulmonary vasoconstriction and pulmonary vascular remodeling.
Pokreisz P, Fleming I, Kiss L, Barbosa-Sicard E, Fisslthaler B, Falck JR, Hammock BD, Kim IH, Szelid Z, Vermeersch P, Gillijns H, Pellens M, Grimminger F, van Zonneveld AJ, Collen D, Busse R, Janssens S. Pokreisz P, et al. Hypertension. 2006 Apr;47(4):762-70. doi: 10.1161/01.HYP.0000208299.62535.58. Epub 2006 Feb 27. Hypertension. 2006. PMID: 16505204 Free PMC article.
Soluble guanylate cyclase-alpha1 deficiency selectively inhibits the pulmonary vasodilator response to nitric oxide and increases the pulmonary vascular remodeling response to chronic hypoxia.
Vermeersch P, Buys E, Pokreisz P, Marsboom G, Ichinose F, Sips P, Pellens M, Gillijns H, Swinnen M, Graveline A, Collen D, Dewerchin M, Brouckaert P, Bloch KD, Janssens S. Vermeersch P, et al. Among authors: pokreisz p. Circulation. 2007 Aug 21;116(8):936-43. doi: 10.1161/CIRCULATIONAHA.106.677245. Epub 2007 Aug 6. Circulation. 2007. PMID: 17679618
Nitric oxide inhalation improves microvascular flow and decreases infarction size after myocardial ischemia and reperfusion.
Liu X, Huang Y, Pokreisz P, Vermeersch P, Marsboom G, Swinnen M, Verbeken E, Santos J, Pellens M, Gillijns H, Van de Werf F, Bloch KD, Janssens S. Liu X, et al. Among authors: pokreisz p. J Am Coll Cardiol. 2007 Aug 21;50(8):808-17. doi: 10.1016/j.jacc.2007.04.069. Epub 2007 Aug 6. J Am Coll Cardiol. 2007. PMID: 17707188 Free article.
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