Wu BN - Search Results

1

Piperazine-designed alpha 1A/alpha 1D-adrenoceptor blocker KMUP-1 and doxazosin provide down-regulation of androgen receptor and PSA in prostatic LNCaP cells growth and specifically in xenografts.

Liu CM, Lo YC, Tai MH, Wu BN, Wu WJ, Chou YH, Chai CY, Huang CH, Chen IJ. Liu CM, et al. Among authors: wu wj, wu bn. Prostate. 2009 May 1;69(6):610-23. doi: 10.1002/pros.20919. Prostate. 2009. PMID: 19143029

2

KMUP-1 relaxes rabbit corpus cavernosum smooth muscle in vitro and in vivo: involvement of cyclic GMP and K(+) channels.

Lin RJ, Wu BN, Lo YC, Shen KP, Lin YT, Huang CH, Chen IJ. Lin RJ, et al. Among authors: wu bn. Br J Pharmacol. 2002 Mar;135(5):1159-66. doi: 10.1038/sj.bjp.0704554. Br J Pharmacol. 2002. PMID: 11877322 Free PMC article.

3

Hypotensive effects of eugenosedin-A with serotonin, alpha- and beta-adrenoceptor antagonistic activities in spontaneously hypertensive and normotensive rats.

Shen KP, Chiu CC, Chen SJ, Chen IJ, Wu BN. Shen KP, et al. Among authors: wu bn. Pharmacology. 2004 Jun;71(2):91-101. doi: 10.1159/000076945. Pharmacology. 2004. PMID: 15118348

4

KMUP-1, a xanthine derivative, induces relaxation of guinea-pig isolated trachea: the role of the epithelium, cyclic nucleotides and K+ channels.

Wu BN, Lin RJ, Lo YC, Shen KP, Wang CC, Lin YT, Chen IJ. Wu BN, et al. Br J Pharmacol. 2004 Aug;142(7):1105-14. doi: 10.1038/sj.bjp.0705791. Epub 2004 Jul 5. Br J Pharmacol. 2004. PMID: 15237094 Free PMC article.

5

Urgosedin inhibits hypotension, hypoglycemia, and pro-inflammatory mediators induced by lipopolysaccharide.

Lo YC, Wang CC, Shen KP, Wu BN, Yu KL, Chen IJ. Lo YC, et al. Among authors: wu bn. J Cardiovasc Pharmacol. 2004 Sep;44(3):363-71. doi: 10.1097/01.fjc.0000137155.63604.7a. J Cardiovasc Pharmacol. 2004. PMID: 15475835

6

Endothelium-dependent and -independent vasorelaxation by a theophylline derivative MCPT: roles of cyclic nucleotides, potassium channel opening and phosphodiesterase inhibition.

Lo YC, Tsou HH, Lin RJ, Wu DC, Wu BN, Lin YT, Chen IJ. Lo YC, et al. Among authors: wu dc, wu bn. Life Sci. 2005 Jan 7;76(8):931-44. doi: 10.1016/j.lfs.2004.10.009. Life Sci. 2005. PMID: 15589969

7

Antioxidant eugenosedin-A protects against lipopolysaccharide-induced hypotension, hyperglycaemia and cytokine immunoreactivity in rats and mice.

Shen KP, Lo YC, Yang RC, Liu HW, Chen IJ, Wu BN. Shen KP, et al. Among authors: wu bn. J Pharm Pharmacol. 2005 Jan;57(1):117-25. doi: 10.1211/0022357055137. J Pharm Pharmacol. 2005. PMID: 15639000

8

KMUP-1 activates BKCa channels in basilar artery myocytes via cyclic nucleotide-dependent protein kinases.

Wu BN, Tu HF, Welsh DG, Chen IJ. Wu BN, et al. Br J Pharmacol. 2005 Nov;146(6):862-71. doi: 10.1038/sj.bjp.0706387. Br J Pharmacol. 2005. PMID: 16151435 Free PMC article.

9

Aortic smooth muscle relaxants KMUP-3 and KMUP-4, two nitrophenylpiperazine derivatives of xanthine, display cGMP-enhancing activity: roles of endothelium, phosphodiesterase, and K+ channel.

Wu BN, Chen IC, Lin RJ, Chiu CC, An LM, Chen IJ. Wu BN, et al. J Cardiovasc Pharmacol. 2005 Nov;46(5):600-8. doi: 10.1097/01.fjc.0000180900.32489.f9. J Cardiovasc Pharmacol. 2005. PMID: 16220066

10

A xanthine-based epithelium-dependent airway relaxant KMUP-3 (7-[2-[4-(4-nitrobenzene)piperazinyl]ethyl]-1,3-dimethylxanthine) increases respiratory performance and protects against tumor necrosis factor-alpha-induced tracheal contraction, involving nitric oxide release and expression of cGMP and protein kinase G.

Lin RJ, Wu BN, Lo YC, An LM, Dai ZK, Lin YT, Tang CS, Chen IJ. Lin RJ, et al. Among authors: wu bn. J Pharmacol Exp Ther. 2006 Feb;316(2):709-17. doi: 10.1124/jpet.105.092171. Epub 2005 Oct 18. J Pharmacol Exp Ther. 2006. PMID: 16234412

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