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Screen for alterations of iron related parameters in N-ethyl-N-nitrosourea-treated mice identified mutant lines with increased plasma ferritin levels.
Rathkolb B, Klempt M, Sabrautzki S, Michel D, Klaften M, Laufs J, Sedlmeier R, Hans W, Fuchs H, Muckenthaler MU, Horsch M, Campagna DR, Fleming M, Hrabé de Angelis M, Wolf E, Aigner B. Rathkolb B, et al. Among authors: sedlmeier r. Biometals. 2015 Apr;28(2):293-306. doi: 10.1007/s10534-015-9824-1. Epub 2015 Jan 31. Biometals. 2015. PMID: 25636453
N-ethyl-N-nitrosourea-based generation of mouse models for mutant G protein-coupled receptors.
Grosse J, Tarnow P, Römpler H, Schneider B, Sedlmeier R, Huffstadt U, Korthaus D, Nehls M, Wattler S, Schöneberg T, Biebermann H, Augustin M. Grosse J, et al. Among authors: sedlmeier r. Physiol Genomics. 2006 Aug 16;26(3):209-17. doi: 10.1152/physiolgenomics.00289.2005. Epub 2006 May 23. Physiol Genomics. 2006. PMID: 16720677 Free article.
Efficient and fast targeted production of murine models based on ENU mutagenesis.
Augustin M, Sedlmeier R, Peters T, Huffstadt U, Kochmann E, Simon D, Schöniger M, Garke-Mayerthaler S, Laufs J, Mayhaus M, Franke S, Klose M, Graupner A, Kurzmann M, Zinser C, Wolf A, Voelkel M, Kellner M, Kilian M, Seelig S, Koppius A, Teubner A, Korthaus D, Nehls M, Wattler S. Augustin M, et al. Among authors: sedlmeier r. Mamm Genome. 2005 Jun;16(6):405-13. doi: 10.1007/s00335-004-3028-2. Mamm Genome. 2005. PMID: 16075367
Random mutagenesis in the mouse as a tool in drug discovery.
Russ A, Stumm G, Augustin M, Sedlmeier R, Wattler S, Nehls M. Russ A, et al. Among authors: sedlmeier r. Drug Discov Today. 2002 Dec 1;7(23):1175-83. doi: 10.1016/s1359-6446(02)02515-1. Drug Discov Today. 2002. PMID: 12547018 Review.
Alopecia in a novel mouse model RCO3 is caused by mK6irs1 deficiency.
Peters T, Sedlmeier R, Büssow H, Runkel F, Lüers GH, Korthaus D, Fuchs H, Hrabé de Angelis M, Stumm G, Russ AP, Porter RM, Augustin M, Franz T. Peters T, et al. Among authors: sedlmeier r. J Invest Dermatol. 2003 Oct;121(4):674-80. doi: 10.1046/j.1523-1747.2003.12491.x. J Invest Dermatol. 2003. PMID: 14632181 Free article.
A mouse model for cystinuria type I.
Peters T, Thaete C, Wolf S, Popp A, Sedlmeier R, Grosse J, Nehls MC, Russ A, Schlueter V. Peters T, et al. Among authors: sedlmeier r. Hum Mol Genet. 2003 Sep 1;12(17):2109-20. doi: 10.1093/hmg/ddg189. Hum Mol Genet. 2003. PMID: 12923163
36 results