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Application of single-molecule spectroscopy in studying enzyme kinetics and mechanism.
Methods Enzymol. 2008;450:129-57. doi: 10.1016/S0076-6879(08)03407-1.
Methods Enzymol. 2008.
PMID: 19152859
Review.
Multiple states of the Tyr318Leu mutant of dihydroorotate dehydrogenase revealed by single-molecule kinetics.
Shi J, Palfey BA, Dertouzos J, Jensen KF, Gafni A, Steel D.
Shi J, et al. Among authors: dertouzos j.
J Am Chem Soc. 2004 Jun 9;126(22):6914-22. doi: 10.1021/ja038902y.
J Am Chem Soc. 2004.
PMID: 15174861
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Conformational dynamics of the isoalloxazine in substrate-free p-hydroxybenzoate hydroxylase: single-molecule studies.
Brender JR, Dertouzos J, Ballou DP, Massey V, Palfey BA, Entsch B, Steel DG, Gafni A.
Brender JR, et al. Among authors: dertouzos j.
J Am Chem Soc. 2005 Dec 28;127(51):18171-8. doi: 10.1021/ja055171o.
J Am Chem Soc. 2005.
PMID: 16366570
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Single-molecule kinetics reveals signatures of half-sites reactivity in dihydroorotate dehydrogenase A catalysis.
Shi J, Dertouzos J, Gafni A, Steel D, Palfey BA.
Shi J, et al. Among authors: dertouzos j.
Proc Natl Acad Sci U S A. 2006 Apr 11;103(15):5775-80. doi: 10.1073/pnas.0510482103. Epub 2006 Apr 3.
Proc Natl Acad Sci U S A. 2006.
PMID: 16585513
Free PMC article.
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