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TRPV1 is activated by both acidic and basic pH.
Dhaka A, Uzzell V, Dubin AE, Mathur J, Petrus M, Bandell M, Patapoutian A. Dhaka A, et al. Among authors: petrus m. J Neurosci. 2009 Jan 7;29(1):153-8. doi: 10.1523/JNEUROSCI.4901-08.2009. J Neurosci. 2009. PMID: 19129393 Free PMC article.
An ion channel essential for sensing chemical damage.
Macpherson LJ, Xiao B, Kwan KY, Petrus MJ, Dubin AE, Hwang S, Cravatt B, Corey DP, Patapoutian A. Macpherson LJ, et al. J Neurosci. 2007 Oct 17;27(42):11412-5. doi: 10.1523/JNEUROSCI.3600-07.2007. J Neurosci. 2007. PMID: 17942735 Free PMC article.
Inflammatory signals enhance piezo2-mediated mechanosensitive currents.
Dubin AE, Schmidt M, Mathur J, Petrus MJ, Xiao B, Coste B, Patapoutian A. Dubin AE, et al. Among authors: petrus mj. Cell Rep. 2012 Sep 27;2(3):511-7. doi: 10.1016/j.celrep.2012.07.014. Epub 2012 Aug 23. Cell Rep. 2012. PMID: 22921401 Free PMC article.
Piezo2 is required for Merkel-cell mechanotransduction.
Woo SH, Ranade S, Weyer AD, Dubin AE, Baba Y, Qiu Z, Petrus M, Miyamoto T, Reddy K, Lumpkin EA, Stucky CL, Patapoutian A. Woo SH, et al. Among authors: petrus m. Nature. 2014 May 29;509(7502):622-6. doi: 10.1038/nature13251. Epub 2014 Apr 6. Nature. 2014. PMID: 24717433 Free PMC article.
Piezo2 is the major transducer of mechanical forces for touch sensation in mice.
Ranade SS, Woo SH, Dubin AE, Moshourab RA, Wetzel C, Petrus M, Mathur J, Bégay V, Coste B, Mainquist J, Wilson AJ, Francisco AG, Reddy K, Qiu Z, Wood JN, Lewin GR, Patapoutian A. Ranade SS, et al. Among authors: petrus m. Nature. 2014 Dec 4;516(7529):121-5. doi: 10.1038/nature13980. Nature. 2014. PMID: 25471886 Free PMC article.
145 results