Schäfer H - Search Results

1

Flexible designs for genomewide association studies.

Scherag A, Hebebrand J, Schäfer H, Müller HH. Scherag A, et al. Among authors: schafer h. Biometrics. 2009 Sep;65(3):815-21. doi: 10.1111/j.1541-0420.2008.01174.x. Epub 2009 Jan 23. Biometrics. 2009. PMID: 19173695

2

Data adaptive interim modification of sample sizes for candidate-gene association studies.

Scherag A, Müller HH, Dempfle A, Hebebrand J, Schäfer H. Scherag A, et al. Among authors: schafer h. Hum Hered. 2003;56(1-3):56-62. doi: 10.1159/000073733. Hum Hered. 2003. PMID: 14614239

3

An overview of statistical approaches for adaptive designs and design modifications.

Schäfer H, Timmesfeld N, Müller HH. Schäfer H, et al. Biom J. 2006 Aug;48(4):507-20. doi: 10.1002/bimj.200510234. Biom J. 2006. PMID: 16972702 Review.

4

Including sampling and phenotyping costs into the optimization of two stage designs for genomewide association studies.

Müller HH, Pahl R, Schäfer H. Müller HH, et al. Among authors: schafer h. Genet Epidemiol. 2007 Dec;31(8):844-52. doi: 10.1002/gepi.20245. Genet Epidemiol. 2007. PMID: 17549751

5

Optimal multistage designs--a general framework for efficient genome-wide association studies.

Pahl R, Schäfer H, Müller HH. Pahl R, et al. Among authors: schafer h. Biostatistics. 2009 Apr;10(2):297-309. doi: 10.1093/biostatistics/kxn036. Epub 2008 Dec 15. Biostatistics. 2009. PMID: 19075295

6

Confidence intervals for genotype relative risks and allele frequencies from the case parent trio design for candidate-gene studies.

Scherag A, Dempfle A, Hinney A, Hebebrand J, Schäfer H. Scherag A, et al. Among authors: schafer h. Hum Hered. 2002;54(4):210-7. doi: 10.1159/000070666. Hum Hered. 2002. PMID: 12771553

7

Reducing sample sizes in genome scans: group sequential study designs with futility stops.

König IR, Schäfer H, Ziegler A, Müller HH. König IR, et al. Among authors: schafer h. Genet Epidemiol. 2003 Dec;25(4):339-49. doi: 10.1002/gepi.10265. Genet Epidemiol. 2003. PMID: 14639703

8

Construction of group sequential designs in clinical trials on the basis of detectable treatment differences.

Schäfer H, Müller HH. Schäfer H, et al. Stat Med. 2004 May 15;23(9):1413-24. doi: 10.1002/sim.1751. Stat Med. 2004. PMID: 15116350

9

A general statistical principle for changing a design any time during the course of a trial.

Müller HH, Schäfer H. Müller HH, et al. Among authors: schafer h. Stat Med. 2004 Aug 30;23(16):2497-508. doi: 10.1002/sim.1852. Stat Med. 2004. PMID: 15287080

10

Evidence for involvement of the vitamin D receptor gene in idiopathic short stature via a genome-wide linkage study and subsequent association studies.

Dempfle A, Wudy SA, Saar K, Hagemann S, Friedel S, Scherag A, Berthold LD, Alzen G, Gortner L, Blum WF, Hinney A, Nürnberg P, Schäfer H, Hebebrand J. Dempfle A, et al. Among authors: schafer h. Hum Mol Genet. 2006 Sep 15;15(18):2772-83. doi: 10.1093/hmg/ddl218. Epub 2006 Aug 11. Hum Mol Genet. 2006. PMID: 16905557

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