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Managing protein flexibility in docking and its applications.
B-Rao C, Subramanian J, Sharma SD. B-Rao C, et al. Among authors: sharma sd. Drug Discov Today. 2009 Apr;14(7-8):394-400. doi: 10.1016/j.drudis.2009.01.003. Epub 2009 Feb 3. Drug Discov Today. 2009. PMID: 19185058 Review.
A fluorinated analog of ISO-1 blocks the recognition and biological function of MIF and is orally efficacious in a murine model of colitis.
Dagia NM, Kamath DV, Bhatt P, Gupte RD, Dadarkar SS, Fonseca L, Agarwal G, Chetrapal-Kunwar A, Balachandran S, Srinivasan S, Bose J, Pari K, B-Rao C, Parkale SS, Gadekar PK, Rodge AH, Mandrekar N, Vishwakarma RA, Sharma S. Dagia NM, et al. Eur J Pharmacol. 2009 Apr 1;607(1-3):201-12. doi: 10.1016/j.ejphar.2009.02.031. Epub 2009 Feb 21. Eur J Pharmacol. 2009. PMID: 19239912
Synthesis and therapeutic evaluation of pyridyl based novel mTOR inhibitors.
Deore V, Yewalkar N, Bhatia D, Desai N, Gupte RD, Dadarkar SS, Jadhav MG, Tannu AA, Bhatt P, Nemmani KV, Vishwakarma RA, Sharma S, Roychowdhury A, Dagia NM, Bhonde MR, Kumar S. Deore V, et al. Bioorg Med Chem Lett. 2009 Jun 1;19(11):2949-52. doi: 10.1016/j.bmcl.2009.04.055. Epub 2009 Apr 18. Bioorg Med Chem Lett. 2009. PMID: 19409777
18F9 (4-(3,6-bis (ethoxycarbonyl)-4,5,6,7-tetrahydrothieno (2,3-c) pyridin-2-ylamino)-4-oxobutanoic acid) enhances insulin-mediated glucose uptake in vitro and exhibits antidiabetic activity in vivo in db/db mice.
Anandharajan R, Sayyed SG, Doshi LS, Dixit P, Chandak PG, Dixit AV, Brahma MK, Deshmukh NJ, Gupte R, Damre A, Suthar J, Padigaru M, Sharma SD, Nemmani KV. Anandharajan R, et al. Among authors: sharma sd. Metabolism. 2009 Oct;58(10):1503-16. doi: 10.1016/j.metabol.2009.04.036. Epub 2009 Jul 15. Metabolism. 2009. PMID: 19608207 Free article.
462 results