Ward SA - Search Results

1

Role of known molecular markers of resistance in the antimalarial potency of piperaquine and dihydroartemisinin in vitro.

Muangnoicharoen S, Johnson DJ, Looareesuwan S, Krudsood S, Ward SA. Muangnoicharoen S, et al. Among authors: ward sa. Antimicrob Agents Chemother. 2009 Apr;53(4):1362-6. doi: 10.1128/AAC.01656-08. Epub 2009 Feb 2. Antimicrob Agents Chemother. 2009. PMID: 19188388 Free PMC article.

2

Development of halofantrine resistance and determination of cross-resistance patterns in Plasmodium falciparum.

Nateghpour M, Ward SA, Howells RE. Nateghpour M, et al. Among authors: ward sa. Antimicrob Agents Chemother. 1993 Nov;37(11):2337-43. doi: 10.1128/AAC.37.11.2337. Antimicrob Agents Chemother. 1993. PMID: 8285616 Free PMC article.

3

Enhancement of drug susceptibility in Plasmodium falciparum in vitro and Plasmodium berghei in vivo by mixed-function oxidase inhibitors.

Ndifor AM, Howells RE, Bray PG, Ngu JL, Ward SA. Ndifor AM, et al. Among authors: ward sa. Antimicrob Agents Chemother. 1993 Jun;37(6):1318-23. doi: 10.1128/AAC.37.6.1318. Antimicrob Agents Chemother. 1993. PMID: 8328780 Free PMC article.

4

The role of drug accumulation in 4-aminoquinoline antimalarial potency. The influence of structural substitution and physicochemical properties.

Hawley SR, Bray PG, O'Neill PM, Park BK, Ward SA. Hawley SR, et al. Among authors: ward sa. Biochem Pharmacol. 1996 Sep 13;52(5):723-33. doi: 10.1016/0006-2952(96)00354-1. Biochem Pharmacol. 1996. PMID: 8765470

5

Manipulation of the N-alkyl substituent in amodiaquine to overcome the verapamil-sensitive chloroquine resistance component.

Hawley SR, Bray PG, O'Neill PM, Naisbitt DJ, Park BK, Ward SA. Hawley SR, et al. Among authors: ward sa. Antimicrob Agents Chemother. 1996 Oct;40(10):2345-9. doi: 10.1128/AAC.40.10.2345. Antimicrob Agents Chemother. 1996. PMID: 8891142 Free PMC article.

6

Mechanism-based design of parasite-targeted artemisinin derivatives: synthesis and antimalarial activity of benzylamino and alkylamino ether analogues of artemisinin.

O'Neill PM, Bishop LP, Storr RC, Hawley SR, Maggs JL, Ward SA, Park BK. O'Neill PM, et al. Among authors: ward sa. J Med Chem. 1996 Oct 25;39(22):4511-4. doi: 10.1021/jm9604944. J Med Chem. 1996. PMID: 8893847

7

Synthesis, antimalarial activity, and molecular modeling of tebuquine analogues.

O'Neill PM, Willock DJ, Hawley SR, Bray PG, Storr RC, Ward SA, Park BK. O'Neill PM, et al. Among authors: ward sa. J Med Chem. 1997 Feb 14;40(4):437-48. doi: 10.1021/jm960370r. J Med Chem. 1997. PMID: 9046333

8

Relationship between antimalarial drug activity, accumulation, and inhibition of heme polymerization in Plasmodium falciparum in vitro.

Hawley SR, Bray PG, Mungthin M, Atkinson JD, O'Neill PM, Ward SA. Hawley SR, et al. Among authors: ward sa. Antimicrob Agents Chemother. 1998 Mar;42(3):682-6. doi: 10.1128/AAC.42.3.682. Antimicrob Agents Chemother. 1998. PMID: 9517951 Free PMC article.

9

Effect of disposition of mannich antimalarial agents on their pharmacology and toxicology.

Ruscoe JE, Tingle MD, O'Neill PM, Ward SA, Park BK. Ruscoe JE, et al. Among authors: ward sa. Antimicrob Agents Chemother. 1998 Sep;42(9):2410-6. doi: 10.1128/AAC.42.9.2410. Antimicrob Agents Chemother. 1998. PMID: 9736572 Free PMC article.

10

Central role of hemoglobin degradation in mechanisms of action of 4-aminoquinolines, quinoline methanols, and phenanthrene methanols.

Mungthin M, Bray PG, Ridley RG, Ward SA. Mungthin M, et al. Among authors: ward sa. Antimicrob Agents Chemother. 1998 Nov;42(11):2973-7. doi: 10.1128/AAC.42.11.2973. Antimicrob Agents Chemother. 1998. PMID: 9797235 Free PMC article.

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