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Metformin selectively attenuates mitochondrial H2O2 emission without affecting respiratory capacity in skeletal muscle of obese rats.
Free Radic Biol Med. 2010 Sep 15;49(6):1082-7. doi: 10.1016/j.freeradbiomed.2010.06.022. Epub 2010 Jun 28.
Free Radic Biol Med. 2010.
PMID: 20600832
Free PMC article.
Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans.
Anderson EJ, Lustig ME, Boyle KE, Woodlief TL, Kane DA, Lin CT, Price JW 3rd, Kang L, Rabinovitch PS, Szeto HH, Houmard JA, Cortright RN, Wasserman DH, Neufer PD.
Anderson EJ, et al. Among authors: price jw 3rd.
J Clin Invest. 2009 Mar;119(3):573-81. doi: 10.1172/JCI37048. Epub 2009 Feb 2.
J Clin Invest. 2009.
PMID: 19188683
Free PMC article.
Clinical Trial.
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