Graham K - Search Results

1

Cytotoxic T cell mechanisms of beta cell destruction in non-obese diabetic mice.

Kay TW, Dudek NL, Graham K, Estella E, Angstetra E, McKenzie MD, Allison J, Thomas HE. Kay TW, et al. Among authors: graham k. Novartis Found Symp. 2008;292:68-78; discussion 78-84, 122-9, 202-3. doi: 10.1002/9780470697405.ch6. Novartis Found Symp. 2008. PMID: 19203093

2

In vivo effects of cytokines on pancreatic beta-cells in models of type I diabetes dependent on CD4(+) T lymphocytes.

Angstetra E, Graham KL, Emmett S, Dudek NL, Darwiche R, Ayala-Perez R, Allison J, Santamaria P, Kay TW, Thomas HE. Angstetra E, et al. Immunol Cell Biol. 2009 Feb;87(2):178-85. doi: 10.1038/icb.2008.81. Epub 2008 Nov 18. Immunol Cell Biol. 2009. PMID: 19015667

3

Interferon signalling in pancreatic beta cells.

Thomas HE, Graham KL, Angstetra E, McKenzie MD, Dudek NL, Kay TW. Thomas HE, et al. Front Biosci (Landmark Ed). 2009 Jan 1;14(2):644-56. doi: 10.2741/3270. Front Biosci (Landmark Ed). 2009. PMID: 19273092 Free article. Review.

4

An indirect role for NK cells in a CD4(+) T-cell-dependent mouse model of type I diabetes.

Angstetra E, Graham KL, Zhao Y, Irvin AE, Elkerbout L, Santamaria P, Slattery RM, Kay TW, Thomas HE. Angstetra E, et al. Immunol Cell Biol. 2012 Feb;90(2):243-7. doi: 10.1038/icb.2011.16. Epub 2011 Mar 8. Immunol Cell Biol. 2012. PMID: 21383770

5

Autoreactive cytotoxic T lymphocytes acquire higher expression of cytotoxic effector markers in the islets of NOD mice after priming in pancreatic lymph nodes.

Graham KL, Krishnamurthy B, Fynch S, Mollah ZU, Slattery R, Santamaria P, Kay TW, Thomas HE. Graham KL, et al. Am J Pathol. 2011 Jun;178(6):2716-25. doi: 10.1016/j.ajpath.2011.02.015. Am J Pathol. 2011. PMID: 21641394 Free PMC article.

6

The pro-apoptotic BH3-only protein Bid is dispensable for development of insulitis and diabetes in the non-obese diabetic mouse.

Mollah ZU, Wali J, McKenzie MD, Krishnamurthy B, Graham KL, Fynch S, Szanyi J, Santamaria P, Brodnicki T, Allison J, Strasser A, Kay TW, Thomas HE. Mollah ZU, et al. Apoptosis. 2011 Aug;16(8):822-30. doi: 10.1007/s10495-011-0615-z. Apoptosis. 2011. PMID: 21644000

7

TNF receptor 1 deficiency increases regulatory T cell function in nonobese diabetic mice.

Chee J, Angstetra E, Mariana L, Graham KL, Carrington EM, Bluethmann H, Santamaria P, Allison J, Kay TW, Krishnamurthy B, Thomas HE. Chee J, et al. J Immunol. 2011 Aug 15;187(4):1702-12. doi: 10.4049/jimmunol.1100511. Epub 2011 Jul 6. J Immunol. 2011. PMID: 21734073

8

Intra-islet proliferation of cytotoxic T lymphocytes contributes to insulitis progression.

Graham KL, Krishnamurthy B, Fynch S, Ayala-Perez R, Slattery RM, Santamaria P, Thomas HE, Kay TW. Graham KL, et al. Eur J Immunol. 2012 Jul;42(7):1717-22. doi: 10.1002/eji.201242435. Epub 2012 Jun 12. Eur J Immunol. 2012. PMID: 22585671 Free article.

9

Granzyme B is dispensable in the development of diabetes in non-obese diabetic mice.

Mollah ZU, Graham KL, Krishnamurthy B, Trivedi P, Brodnicki TC, Trapani JA, Kay TW, Thomas HE. Mollah ZU, et al. PLoS One. 2012;7(7):e40357. doi: 10.1371/journal.pone.0040357. Epub 2012 Jul 9. PLoS One. 2012. PMID: 22792290 Free PMC article.

10

Pathogenic mechanisms in type 1 diabetes: the islet is both target and driver of disease.

Graham KL, Sutherland RM, Mannering SI, Zhao Y, Chee J, Krishnamurthy B, Thomas HE, Lew AM, Kay TW. Graham KL, et al. Rev Diabet Stud. 2012 Winter;9(4):148-68. doi: 10.1900/RDS.2012.9.148. Epub 2012 Dec 28. Rev Diabet Stud. 2012. PMID: 23804258 Free PMC article. Review.

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