Ebert U - Search Results

1

Structural characterization of a soluble amyloid beta-peptide oligomer.

Yu L, Edalji R, Harlan JE, Holzman TF, Lopez AP, Labkovsky B, Hillen H, Barghorn S, Ebert U, Richardson PL, Miesbauer L, Solomon L, Bartley D, Walter K, Johnson RW, Hajduk PJ, Olejniczak ET. Yu L, et al. Among authors: ebert u. Biochemistry. 2009 Mar 10;48(9):1870-7. doi: 10.1021/bi802046n. Biochemistry. 2009. PMID: 19216516

2

Globular amyloid beta-peptide oligomer - a homogenous and stable neuropathological protein in Alzheimer's disease.

Barghorn S, Nimmrich V, Striebinger A, Krantz C, Keller P, Janson B, Bahr M, Schmidt M, Bitner RS, Harlan J, Barlow E, Ebert U, Hillen H. Barghorn S, et al. Among authors: ebert u. J Neurochem. 2005 Nov;95(3):834-47. doi: 10.1111/j.1471-4159.2005.03407.x. Epub 2005 Aug 31. J Neurochem. 2005. PMID: 16135089 Free article.

3

Amyloid beta oligomers (A beta(1-42) globulomer) suppress spontaneous synaptic activity by inhibition of P/Q-type calcium currents.

Nimmrich V, Grimm C, Draguhn A, Barghorn S, Lehmann A, Schoemaker H, Hillen H, Gross G, Ebert U, Bruehl C. Nimmrich V, et al. Among authors: ebert u. J Neurosci. 2008 Jan 23;28(4):788-97. doi: 10.1523/JNEUROSCI.4771-07.2008. J Neurosci. 2008. PMID: 18216187 Free PMC article.

4

Generation and therapeutic efficacy of highly oligomer-specific beta-amyloid antibodies.

Hillen H, Barghorn S, Striebinger A, Labkovsky B, Müller R, Nimmrich V, Nolte MW, Perez-Cruz C, van der Auwera I, van Leuven F, van Gaalen M, Bespalov AY, Schoemaker H, Sullivan JP, Ebert U. Hillen H, et al. Among authors: ebert u. J Neurosci. 2010 Aug 4;30(31):10369-79. doi: 10.1523/JNEUROSCI.5721-09.2010. J Neurosci. 2010. PMID: 20685980 Free PMC article.

5

Magnetic resonance imaging detection and time course of cerebral microhemorrhages during passive immunotherapy in living amyloid precursor protein transgenic mice.

Luo F, Rustay NR, Seifert T, Roesner B, Hradil V, Hillen H, Ebert U, Severin JM, Cox BF, Llano DA, Day M, Fox GB. Luo F, et al. Among authors: ebert u. J Pharmacol Exp Ther. 2010 Dec;335(3):580-8. doi: 10.1124/jpet.110.172932. Epub 2010 Sep 7. J Pharmacol Exp Ther. 2010. PMID: 20823195

6

Is Alzheimer's disease a result of presynaptic failure? Synaptic dysfunctions induced by oligomeric beta-amyloid.

Nimmrich V, Ebert U. Nimmrich V, et al. Among authors: ebert u. Rev Neurosci. 2009;20(1):1-12. doi: 10.1515/revneuro.2009.20.1.1. Rev Neurosci. 2009. PMID: 19526730 Review.

7

Synaptic transmission is impaired prior to plaque formation in amyloid precursor protein-overexpressing mice without altering behaviorally-correlated sharp wave-ripple complexes.

Hermann D, Both M, Ebert U, Gross G, Schoemaker H, Draguhn A, Wicke K, Nimmrich V. Hermann D, et al. Among authors: ebert u. Neuroscience. 2009 Sep 15;162(4):1081-90. doi: 10.1016/j.neuroscience.2009.05.044. Epub 2009 May 27. Neuroscience. 2009. PMID: 19477243

8

Characterization of 7- and 19-month-old Tg2576 mice using multimodal in vivo imaging: limitations as a translatable model of Alzheimer's disease.

Luo F, Rustay NR, Ebert U, Hradil VP, Cole TB, Llano DA, Mudd SR, Zhang Y, Fox GB, Day M. Luo F, et al. Among authors: ebert u. Neurobiol Aging. 2012 May;33(5):933-44. doi: 10.1016/j.neurobiolaging.2010.08.005. Epub 2010 Oct 18. Neurobiol Aging. 2012. PMID: 20961663

9

An ELISA-based method for the quantification of incorporated BrdU as a measure of cell proliferation in vivo.

Behl B, Klos M, Serr M, Ebert U, Janson B, Drescher K, Gross G, Schoemaker H. Behl B, et al. Among authors: ebert u. J Neurosci Methods. 2006 Nov 15;158(1):37-49. doi: 10.1016/j.jneumeth.2006.05.011. Epub 2006 Jun 15. J Neurosci Methods. 2006. PMID: 16780957

10

Failed trials for central nervous system disorders do not necessarily invalidate preclinical models and drug targets.

Bespalov A, Steckler T, Altevogt B, Koustova E, Skolnick P, Deaver D, Millan MJ, Bastlund JF, Doller D, Witkin J, Moser P, O'Donnell P, Ebert U, Geyer MA, Prinssen E, Ballard T, Macleod M. Bespalov A, et al. Among authors: ebert u. Nat Rev Drug Discov. 2016 Jul;15(7):516. doi: 10.1038/nrd.2016.88. Epub 2016 Jun 17. Nat Rev Drug Discov. 2016. PMID: 27312728 No abstract available.

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