Husain SS - Search Results

1

Time-resolved photolabeling of the nicotinic acetylcholine receptor by [3H]azietomidate, an open-state inhibitor.

Chiara DC, Hong FH, Arevalo E, Husain SS, Miller KW, Forman SA, Cohen JB. Chiara DC, et al. Among authors: husain ss. Mol Pharmacol. 2009 May;75(5):1084-95. doi: 10.1124/mol.108.054353. Epub 2009 Feb 13. Mol Pharmacol. 2009. PMID: 19218367 Free PMC article.

2

2-(3-Methyl-3H-diaziren-3-yl)ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate: a derivative of the stereoselective general anesthetic etomidate for photolabeling ligand-gated ion channels.

Husain SS, Ziebell MR, Ruesch D, Hong F, Arevalo E, Kosterlitz JA, Olsen RW, Forman SA, Cohen JB, Miller KW. Husain SS, et al. J Med Chem. 2003 Mar 27;46(7):1257-65. doi: 10.1021/jm020465v. J Med Chem. 2003. PMID: 12646036

3

Identification of binding sites in the nicotinic acetylcholine receptor for [3H]azietomidate, a photoactivatable general anesthetic.

Ziebell MR, Nirthanan S, Husain SS, Miller KW, Cohen JB. Ziebell MR, et al. Among authors: husain ss. J Biol Chem. 2004 Apr 23;279(17):17640-9. doi: 10.1074/jbc.M313886200. Epub 2004 Feb 3. J Biol Chem. 2004. PMID: 14761946 Free article.

4

Identification of binding sites in the nicotinic acetylcholine receptor for TDBzl-etomidate, a photoreactive positive allosteric effector.

Nirthanan S, Garcia G 3rd, Chiara DC, Husain SS, Cohen JB. Nirthanan S, et al. Among authors: husain ss. J Biol Chem. 2008 Aug 8;283(32):22051-62. doi: 10.1074/jbc.M801332200. Epub 2008 Jun 4. J Biol Chem. 2008. PMID: 18524766 Free PMC article.

5

Multiple transmembrane binding sites for p-trifluoromethyldiazirinyl-etomidate, a photoreactive Torpedo nicotinic acetylcholine receptor allosteric inhibitor.

Hamouda AK, Stewart DS, Husain SS, Cohen JB. Hamouda AK, et al. Among authors: husain ss. J Biol Chem. 2011 Jun 10;286(23):20466-77. doi: 10.1074/jbc.M111.219071. Epub 2011 Apr 15. J Biol Chem. 2011. PMID: 21498509 Free PMC article.

6

Identification of sites of incorporation in the nicotinic acetylcholine receptor of a photoactivatible general anesthetic.

Pratt MB, Husain SS, Miller KW, Cohen JB. Pratt MB, et al. Among authors: husain ss. J Biol Chem. 2000 Sep 22;275(38):29441-51. doi: 10.1074/jbc.M004710200. J Biol Chem. 2000. PMID: 10859324 Free article.

7

Synthesis of trifluoromethylaryl diazirine and benzophenone derivatives of etomidate that are potent general anesthetics and effective photolabels for probing sites on ligand-gated ion channels.

Husain SS, Nirthanan S, Ruesch D, Solt K, Cheng Q, Li GD, Arevalo E, Olsen RW, Raines DE, Forman SA, Cohen JB, Miller KW. Husain SS, et al. J Med Chem. 2006 Aug 10;49(16):4818-25. doi: 10.1021/jm051207b. J Med Chem. 2006. PMID: 16884293

8

Identification of a GABAA receptor anesthetic binding site at subunit interfaces by photolabeling with an etomidate analog.

Li GD, Chiara DC, Sawyer GW, Husain SS, Olsen RW, Cohen JB. Li GD, et al. Among authors: husain ss. J Neurosci. 2006 Nov 8;26(45):11599-605. doi: 10.1523/JNEUROSCI.3467-06.2006. J Neurosci. 2006. PMID: 17093081 Free PMC article.

9

Methoxycarbonyl-etomidate: a novel rapidly metabolized and ultra-short-acting etomidate analogue that does not produce prolonged adrenocortical suppression.

Cotten JF, Husain SS, Forman SA, Miller KW, Kelly EW, Nguyen HH, Raines DE. Cotten JF, et al. Among authors: husain ss. Anesthesiology. 2009 Aug;111(2):240-9. doi: 10.1097/ALN.0b013e3181ae63d1. Anesthesiology. 2009. PMID: 19625798 Free PMC article.

10

Carboetomidate: a pyrrole analog of etomidate designed not to suppress adrenocortical function.

Cotten JF, Forman SA, Laha JK, Cuny GD, Husain SS, Miller KW, Nguyen HH, Kelly EW, Stewart D, Liu A, Raines DE. Cotten JF, et al. Among authors: husain ss. Anesthesiology. 2010 Mar;112(3):637-44. doi: 10.1097/ALN.0b013e3181cf40ed. Anesthesiology. 2010. PMID: 20179500 Free PMC article.

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