Coupar IM - Search Results

1

Synthesis and preliminary screening of novel indole-3-methanamines as 5-HT4 receptor ligands.

Hanna-Elias A, Manallack DT, Berque-Bestel I, Irving HR, Coupar IM, Iskander MN. Hanna-Elias A, et al. Among authors: coupar im. Eur J Med Chem. 2009 Jul;44(7):2952-9. doi: 10.1016/j.ejmech.2009.01.015. Epub 2009 Jan 24. Eur J Med Chem. 2009. PMID: 19223092

2

Synthesis, testing and structure-activity studies on a library of 5-HT₄ ligands.

Hanna-Elias A, Manallack DT, Levit A, Nguyen W, Ayad F, Perera G, Shapiro M, Irving HR, Coupar IM, Iskander MN. Hanna-Elias A, et al. Among authors: coupar im. Med Chem. 2010 Nov;6(6):344-54. doi: 10.2174/157340610793563965. Med Chem. 2010. PMID: 21175422

3

Assessment of the pharmacological properties of 5-methoxyindole derivatives at 5-HT4 receptors.

Coupar IM, Irving HR, Manallack DT, Tan YY, Ayad F, Iulio JD, Tochon-Danguy N, Iskander MN. Coupar IM, et al. J Pharm Pharmacol. 2012 Aug;64(8):1099-106. doi: 10.1111/j.2042-7158.2012.01500.x. Epub 2012 Mar 16. J Pharm Pharmacol. 2012. PMID: 22775213

4

Optimization of a pharmacophore model for 5-HT4 agonists using CoMFA and receptor based alignment.

Iskander MN, Leung LM, Buley T, Ayad F, Di Iulio J, Tan YY, Coupar IM. Iskander MN, et al. Among authors: coupar im. Eur J Med Chem. 2006 Jan;41(1):16-26. doi: 10.1016/j.ejmech.2005.07.017. Epub 2005 Nov 15. Eur J Med Chem. 2006. PMID: 16293350

5

The use of tripeptides for lead discovery of 5-HT4 receptor ligands.

Hanna-Elias A, Thompson PE, Manallack DT, Irving HR, Coupar IM, Berque-Bestel I, Iskander MN. Hanna-Elias A, et al. Among authors: coupar im. Protein Pept Lett. 2009;16(7):805-9. doi: 10.2174/092986609788681805. Protein Pept Lett. 2009. PMID: 19601910

6

Synthesis and preliminary screening of novel tryptamines as 5-HT4 receptor ligands.

Hanna-Elias A, Manallack DT, Berque-Bestel I, Irving HR, Coupar IM, Iskander MN. Hanna-Elias A, et al. Among authors: coupar im. Curr Med Chem. 2010;17(25):2775-87. doi: 10.2174/092986710791859351. Curr Med Chem. 2010. PMID: 20586717

7

Effects of the novel 5-HT3 agonist MKC-733 on the rat, mouse and guinea pig digestive tract.

Chetty N, Irving HR, Coupar IM. Chetty N, et al. Among authors: coupar im. Pharmacology. 2008;81(2):104-9. doi: 10.1159/000109984. Epub 2007 Oct 19. Pharmacology. 2008. PMID: 17952012

8

Investigations into the binding affinities of different human 5-HT4 receptor splice variants.

Irving HR, Tochon-Danguy N, Chinkwo KA, Li JG, Grabbe C, Shapiro M, Pouton CW, Coupar IM. Irving HR, et al. Among authors: coupar im. Pharmacology. 2010;85(4):224-33. doi: 10.1159/000280418. Epub 2010 Mar 17. Pharmacology. 2010. PMID: 20299822

9

Tissue dependent differences in G-protein coupled receptor kinases associated with 5-HT4 receptor desensitization in the rat gastro-intestinal tract.

Nedi T, White PJ, Coupar IM, Irving HR. Nedi T, et al. Among authors: coupar im. Biochem Pharmacol. 2011 Jan 1;81(1):123-33. doi: 10.1016/j.bcp.2010.09.003. Epub 2010 Sep 15. Biochem Pharmacol. 2011. PMID: 20836992

10

Effect of the 5-HT₄ receptor agonist tegaserod on the expression of GRK2 and GRK6 in the rat gastrointestinal tract.

Nedi T, White PJ, Coupar IM, Irving HR. Nedi T, et al. Among authors: coupar im. BMC Res Notes. 2018 Jun 8;11(1):362. doi: 10.1186/s13104-018-3495-2. BMC Res Notes. 2018. PMID: 29884229 Free PMC article.

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