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Page 1
Inhibitors of hepatitis C virus polymerase: synthesis and biological characterization of unsymmetrical dialkyl-hydroxynaphthalenoyl-benzothiadiazines.
Wagner R, Larson DP, Beno DW, Bosse TD, Darbyshire JF, Gao Y, Gates BD, He W, Henry RF, Hernandez LE, Hutchinson DK, Jiang WW, Kati WM, Klein LL, Koev G, Kohlbrenner W, Krueger AC, Liu J, Liu Y, Long MA, Maring CJ, Masse SV, Middleton T, Montgomery DA, Pratt JK, Stuart P, Molla A, Kempf DJ. Wagner R, et al. Among authors: long ma. J Med Chem. 2009 Mar 26;52(6):1659-69. doi: 10.1021/jm8010965. J Med Chem. 2009. PMID: 19226162
Activity of a potent hepatitis C virus polymerase inhibitor in the chimpanzee model.
Chen CM, He Y, Lu L, Lim HB, Tripathi RL, Middleton T, Hernandez LE, Beno DW, Long MA, Kati WM, Bosse TD, Larson DP, Wagner R, Lanford RE, Kohlbrenner WE, Kempf DJ, Pilot-Matias TJ, Molla A. Chen CM, et al. Among authors: long ma. Antimicrob Agents Chemother. 2007 Dec;51(12):4290-6. doi: 10.1128/AAC.00723-07. Epub 2007 Oct 1. Antimicrob Agents Chemother. 2007. PMID: 17908950 Free PMC article.
Discovery of 2-[4-{{2-(2S,5R)-2-cyano-5-ethynyl-1-pyrrolidinyl]-2-oxoethyl]amino]- 4-methyl-1-piperidinyl]-4-pyridinecarboxylic acid (ABT-279): a very potent, selective, effective, and well-tolerated inhibitor of dipeptidyl peptidase-IV, useful for the treatment of diabetes.
Madar DJ, Kopecka H, Pireh D, Yong H, Pei Z, Li X, Wiedeman PE, Djuric SW, Von Geldern TW, Fickes MG, Bhagavatula L, McDermott T, Wittenberger S, Richards SJ, Longenecker KL, Stewart KD, Lubben TH, Ballaron SJ, Stashko MA, Long MA, Wells H, Zinker BA, Mika AK, Beno DW, Kempf-Grote AJ, Polakowski J, Segreti J, Reinhart GA, Fryer RM, Sham HL, Trevillyan JM. Madar DJ, et al. Among authors: long ma. J Med Chem. 2006 Oct 19;49(21):6416-20. doi: 10.1021/jm060777o. J Med Chem. 2006. PMID: 17034148
Discovery, structure-activity relationship, and pharmacological evaluation of (5-substituted-pyrrolidinyl-2-carbonyl)-2-cyanopyrrolidines as potent dipeptidyl peptidase IV inhibitors.
Pei Z, Li X, Longenecker K, von Geldern TW, Wiedeman PE, Lubben TH, Zinker BA, Stewart K, Ballaron SJ, Stashko MA, Mika AK, Beno DW, Long M, Wells H, Kempf-Grote AJ, Madar DJ, McDermott TS, Bhagavatula L, Fickes MG, Pireh D, Solomon LR, Lake MR, Edalji R, Fry EH, Sham HL, Trevillyan JM. Pei Z, et al. Among authors: long m. J Med Chem. 2006 Jun 15;49(12):3520-35. doi: 10.1021/jm051283e. J Med Chem. 2006. PMID: 16759095
Bose-Einstein condensation of a two-magnon bound state in a spin-1 triangular lattice.
Sheng J, Mei JW, Wang L, Xu X, Jiang W, Xu L, Ge H, Zhao N, Li T, Candini A, Xi B, Zhao J, Fu Y, Yang J, Zhang Y, Biasiol G, Wang S, Zhu J, Miao P, Tong X, Yu D, Mole R, Cui Y, Ma L, Zhang Z, Ouyang Z, Tong W, Podlesnyak A, Wang L, Ye F, Yu D, Yu W, Wu L, Wang Z. Sheng J, et al. Among authors: ma l. Nat Mater. 2025 Jan 20. doi: 10.1038/s41563-024-02071-z. Online ahead of print. Nat Mater. 2025. PMID: 39833392
670 results