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Delayed treatment with W1-mAb, a chimpanzee-derived monoclonal antibody against protective antigen, reduces mortality from challenges with anthrax edema or lethal toxin in rats and with anthrax spores in mice.
Altaweel L, Chen Z, Moayeri M, Cui X, Li Y, Su J, Fitz Y, Johnson S, Leppla SH, Purcell R, Eichacker PQ. Altaweel L, et al. Among authors: su j. Crit Care Med. 2011 Jun;39(6):1439-47. doi: 10.1097/CCM.0b013e3182120691. Crit Care Med. 2011. PMID: 21336113 Free PMC article.
Bacillus anthracis edema but not lethal toxin challenge in rats is associated with depressed myocardial function in hearts isolated and tested in a Langendorff system.
Li Y, Abu-Asab M, Su J, Qiu P, Feng J, Ohanjanian L, Kumar HS, Fitz Y, Eichacker PQ, Cui X. Li Y, et al. Among authors: su j. Am J Physiol Heart Circ Physiol. 2015 Jun 15;308(12):H1592-602. doi: 10.1152/ajpheart.00851.2014. Epub 2015 Apr 10. Am J Physiol Heart Circ Physiol. 2015. PMID: 25862834 Free PMC article.
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