Haynes NM - Search Results

1

The Lewis-Y carbohydrate antigen is expressed by many human tumors and can serve as a target for genetically redirected T cells despite the presence of soluble antigen in serum.

Westwood JA, Murray WK, Trivett M, Haynes NM, Solomon B, Mileshkin L, Ball D, Michael M, Burman A, Mayura-Guru P, Trapani JA, Peinert S, Hönemann D, Miles Prince H, Scott AM, Smyth MJ, Darcy PK, Kershaw MH. Westwood JA, et al. Among authors: haynes nm. J Immunother. 2009 Apr;32(3):292-301. doi: 10.1097/CJI.0b013e31819b7c8e. J Immunother. 2009. PMID: 19242371

2

Fas-ligand-mediated lysis of erbB-2-expressing tumour cells by redirected cytotoxic T lymphocytes.

Haynes NM, Smyth MJ, Kershaw MH, Trapani JA, Darcy PK. Haynes NM, et al. Cancer Immunol Immunother. 1999 Jan;47(5):278-86. doi: 10.1007/s002620050532. Cancer Immunol Immunother. 1999. PMID: 10022472 Free PMC article.

3

Multiple deficiencies underlie NK cell inactivity in lymphotoxin-alpha gene-targeted mice.

Smyth MJ, Johnstone RW, Cretney E, Haynes NM, Sedgwick JD, Korner H, Poulton LD, Baxter AG. Smyth MJ, et al. Among authors: haynes nm. J Immunol. 1999 Aug 1;163(3):1350-3. J Immunol. 1999. PMID: 10415034

4

Redirected perforin-dependent lysis of colon carcinoma by ex vivo genetically engineered CTL.

Darcy PK, Haynes NM, Snook MB, Trapani JA, Cerruti L, Jane SM, Smyth MJ. Darcy PK, et al. Among authors: haynes nm. J Immunol. 2000 Apr 1;164(7):3705-12. doi: 10.4049/jimmunol.164.7.3705. J Immunol. 2000. PMID: 10725729

5

Redirecting mouse CTL against colon carcinoma: superior signaling efficacy of single-chain variable domain chimeras containing TCR-zeta vs Fc epsilon RI-gamma.

Haynes NM, Snook MB, Trapani JA, Cerruti L, Jane SM, Smyth MJ, Darcy PK. Haynes NM, et al. J Immunol. 2001 Jan 1;166(1):182-7. doi: 10.4049/jimmunol.166.1.182. J Immunol. 2001. PMID: 11123291

6

Single-chain antigen recognition receptors that costimulate potent rejection of established experimental tumors.

Haynes NM, Trapani JA, Teng MW, Jackson JT, Cerruti L, Jane SM, Kershaw MH, Smyth MJ, Darcy PK. Haynes NM, et al. Blood. 2002 Nov 1;100(9):3155-63. doi: 10.1182/blood-2002-04-1041. Blood. 2002. PMID: 12384413 Free article.

7

Rejection of syngeneic colon carcinoma by CTLs expressing single-chain antibody receptors codelivering CD28 costimulation.

Haynes NM, Trapani JA, Teng MW, Jackson JT, Cerruti L, Jane SM, Kershaw MH, Smyth MJ, Darcy PK. Haynes NM, et al. J Immunol. 2002 Nov 15;169(10):5780-6. doi: 10.4049/jimmunol.169.10.5780. J Immunol. 2002. PMID: 12421958

8

A functional role for CD28 costimulation in tumor recognition by single-chain receptor-modified T cells.

Moeller M, Haynes NM, Trapani JA, Teng MW, Jackson JT, Tanner JE, Cerutti L, Jane SM, Kershaw MH, Smyth MJ, Darcy PK. Moeller M, et al. Among authors: haynes nm. Cancer Gene Ther. 2004 May;11(5):371-9. doi: 10.1038/sj.cgt.7700710. Cancer Gene Ther. 2004. PMID: 15060573

9

Gene-engineered T cells as a superior adjuvant therapy for metastatic cancer.

Kershaw MH, Jackson JT, Haynes NM, Teng MW, Moeller M, Hayakawa Y, Street SE, Cameron R, Tanner JE, Trapani JA, Smyth MJ, Darcy PK. Kershaw MH, et al. Among authors: haynes nm. J Immunol. 2004 Aug 1;173(3):2143-50. doi: 10.4049/jimmunol.173.3.2143. J Immunol. 2004. PMID: 15265951

10

Adoptive transfer of gene-engineered CD4+ helper T cells induces potent primary and secondary tumor rejection.

Moeller M, Haynes NM, Kershaw MH, Jackson JT, Teng MW, Street SE, Cerutti L, Jane SM, Trapani JA, Smyth MJ, Darcy PK. Moeller M, et al. Among authors: haynes nm. Blood. 2005 Nov 1;106(9):2995-3003. doi: 10.1182/blood-2004-12-4906. Epub 2005 Jul 19. Blood. 2005. PMID: 16030195 Free article.

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