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Enhanced Rap1 activation and insulin secretagogue properties of an acetoxymethyl ester of an Epac-selective cyclic AMP analog in rat INS-1 cells: studies with 8-pCPT-2'-O-Me-cAMP-AM.
Chepurny OG, Leech CA, Kelley GG, Dzhura I, Dzhura E, Li X, Rindler MJ, Schwede F, Genieser HG, Holz GG. Chepurny OG, et al. Among authors: kelley gg. J Biol Chem. 2009 Apr 17;284(16):10728-36. doi: 10.1074/jbc.M900166200. Epub 2009 Feb 25. J Biol Chem. 2009. PMID: 19244230 Free PMC article.
PKA-dependent potentiation of glucose-stimulated insulin secretion by Epac activator 8-pCPT-2'-O-Me-cAMP-AM in human islets of Langerhans.
Chepurny OG, Kelley GG, Dzhura I, Leech CA, Roe MW, Dzhura E, Li X, Schwede F, Genieser HG, Holz GG. Chepurny OG, et al. Among authors: kelley gg. Am J Physiol Endocrinol Metab. 2010 Mar;298(3):E622-33. doi: 10.1152/ajpendo.00630.2009. Epub 2009 Dec 15. Am J Physiol Endocrinol Metab. 2010. PMID: 20009023 Free PMC article.
Epac2-dependent mobilization of intracellular Ca²+ by glucagon-like peptide-1 receptor agonist exendin-4 is disrupted in β-cells of phospholipase C-ε knockout mice.
Dzhura I, Chepurny OG, Kelley GG, Leech CA, Roe MW, Dzhura E, Afshari P, Malik S, Rindler MJ, Xu X, Lu Y, Smrcka AV, Holz GG. Dzhura I, et al. Among authors: kelley gg. J Physiol. 2010 Dec 15;588(Pt 24):4871-89. doi: 10.1113/jphysiol.2010.198424. Epub 2010 Nov 1. J Physiol. 2010. PMID: 21041529 Free PMC article.
40 results