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PEGylation of osteoprotegerin/osteoclastogenesis inhibitory factor (OPG/OCIF) results in decreased uptake into rats and human liver.
Saito-Yabe M, Kasuya Y, Yoshigae Y, Yamamura N, Suzuki Y, Fukuda N, Honma M, Yano K, Mochizuki S, Okada F, Okada A, Nagayama Y, Tsuda E, Fischer T, Höpner U, Zaja S, Mueller J, Okada J, Kurihara A, Ikeda T, Okazaki O. Saito-Yabe M, et al. Among authors: kurihara a. J Pharm Pharmacol. 2010 Aug;62(8):985-94. doi: 10.1111/j.2042-7158.2010.01120.x. J Pharm Pharmacol. 2010. PMID: 20663032
Use of an intravenous microdose of 14C-labeled drug and accelerator mass spectrometry to measure absolute oral bioavailability in dogs; cross-comparison of assay methods by accelerator mass spectrometry and liquid chromatography-tandem mass spectrometry.
Miyaji Y, Ishizuka T, Kawai K, Hamabe Y, Miyaoka T, Oh-hara T, Ikeda T, Kurihara A. Miyaji Y, et al. Among authors: kurihara a. Drug Metab Pharmacokinet. 2009;24(2):130-8. doi: 10.2133/dmpk.24.130. Drug Metab Pharmacokinet. 2009. PMID: 19430168 Free article.
217 results